C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 1, group D, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021775 Nr1d2 10090 - 14:18204054-18239127 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000090543 Nr1d2-001 18204054-18239127 protein_coding
  ENSMUST00000143308 Nr1d2-002 18214536-18239031 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000090543ENSMUST00000143308
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000090543 6.068±1.15 6.712±1.30 17.129±7.31 5.868±7.04 3.475±0.80 3.237±0.90 9.123±0.60 7.846±0.76 2.156±1.55 10.615±1.77 18.831±5.22 7.800±5.39 1.495±0.54 1.843±0.31
ENSMUST00000143308 4.854±1.19 60.267±5.11 N/A N/A 8.288±5.29 5.344±2.11 N/A 8.116±3.78 2.012±0.72 24.928±6.05 N/A 19.160±5.25 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004887 IEA thyroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0019216 IMP regulation of lipid metabolic process
GO:0030522 IEA intracellular receptor signaling pathway
GO:0042752 IDA regulation of circadian rhythm
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0048511 IEA rhythmic process
GO:0050727 IMP regulation of inflammatory response
GO:0055088 IMP lipid homeostasis
GO:2000505 IMP regulation of energy homeostasis
GO:2001014 IMP regulation of skeletal muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003820 nr1d2a nuclear receptor subfamily 1, group D, member 2a protein_coding Danio_rerio
ENSDARG00000009594 nr1d2b nuclear receptor subfamily 1, group D, member 2b protein_coding Danio_rerio
ENSG00000174738 NR1D2 nuclear receptor subfamily 1, group D, member 2 protein_coding Homo_sapiens

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