C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ribonucleotide reductase M2 B (TP53 inducible)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022292 Rrm2b 10090 - 15:37923952-37961318 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022901 Rrm2b-001 37923952-37961103 protein_coding
  ENSMUST00000127362 Rrm2b-002 37945048-37955138 retained_intron
  ENSMUST00000137636 Rrm2b-003 37927245-37960891 protein_coding
  ENSMUST00000144498 Rrm2b-008 37931637-37960929 nonsense_mediated_decay
  ENSMUST00000145155 Rrm2b-006 37946752-37961318 protein_coding
  ENSMUST00000145175 Rrm2b-007 37945153-37960849 protein_coding
  ENSMUST00000146821 Rrm2b-004 37927245-37960891 protein_coding
  ENSMUST00000153481 Rrm2b-005 37927245-37960891 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022901ENSMUST00000127362ENSMUST00000137636ENSMUST00000144498ENSMUST00000145175
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022901 1.309±0.58 1.881±0.78 4.841±0.01 1.516±0.33 0.961±0.30 0.709±0.00 2.479±0.76 1.478±0.41 0.744±0.32 3.695±1.99 4.031±0.97 3.150±1.28 1.942±0.67 0.404±0.29
ENSMUST00000127362 N/A N/A N/A N/A N/A N/A N/A N/A 0.253±0.08 N/A N/A N/A N/A N/A
ENSMUST00000137636 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.511±0.00
ENSMUST00000144498 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.311±0.00
ENSMUST00000145175 N/A N/A N/A N/A N/A 0.682±0.29 N/A N/A N/A N/A N/A N/A N/A 0.572±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00000S CIL_00000S_0002 CGP 15:37923952-38078853

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0003014 IMP renal system process
GO:0004748 IDA ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IC mitochondrion
GO:0006264 IMP mitochondrial DNA replication
GO:0006281 IMP DNA repair
GO:0006979 IMP response to oxidative stress
GO:0009186 IEA deoxyribonucleoside diphosphate metabolic process
GO:0009200 IMP deoxyribonucleoside triphosphate metabolic process
GO:0009263 IDA deoxyribonucleotide biosynthetic process
GO:0046872 IEA metal ion binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome
GO:1902254 IMP negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033367 rrm2b ribonucleotide reductase M2 b protein_coding Danio_rerio
ENSG00000048392 RRM2B ribonucleotide reductase M2 B (TP53 inducible) protein_coding Homo_sapiens

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