C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ribonucleotide reductase M2 B (TP53 inducible)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022901 Rrm2b-001 ENSMUSG00000022292 10090 - 15:37923952-37961103 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022901
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022901 1.309±0.58 1.881±0.78 4.841±0.01 1.516±0.33 0.961±0.30 0.709±0.00 2.479±0.76 1.478±0.41 0.744±0.32 3.695±1.99 4.031±0.97 3.150±1.28 1.942±0.67 0.404±0.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00000S CIL_00000S_0002 CGP 15:37923952-38078853

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 IMP kidney development
GO:0003014 IMP renal system process
GO:0004748 IDA ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IC mitochondrion
GO:0006264 IMP mitochondrial DNA replication
GO:0006281 IMP DNA repair
GO:0006979 IMP response to oxidative stress
GO:0009186 IEA deoxyribonucleoside diphosphate metabolic process
GO:0009200 IMP deoxyribonucleoside triphosphate metabolic process
GO:0009263 IDA deoxyribonucleotide biosynthetic process
GO:0046872 IEA metal ion binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome
GO:1902254 IMP negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000251810 RRM2B-001 protein_coding Homo_sapiens 0 1437
ENST00000395910 RRM2B-009 retained_intron Homo_sapiens 0 523
ENST00000395912 RRM2B-005 protein_coding Homo_sapiens 0 1214
ENST00000517517 RRM2B-006 retained_intron Homo_sapiens 0 228
ENST00000519125 RRM2B-008 retained_intron Homo_sapiens 0 483
ENST00000519317 RRM2B-004 protein_coding Homo_sapiens 0 529
ENST00000519962 RRM2B-002 protein_coding Homo_sapiens 0 226
ENST00000522368 RRM2B-003 protein_coding Homo_sapiens 0 1367
ENST00000522394 RRM2B-011 nonsense_mediated_decay Homo_sapiens 0 401
ENST00000523957 RRM2B-007 nonsense_mediated_decay Homo_sapiens 0 479
ENST00000621845 RRM2B-201 protein_coding Homo_sapiens 0 1367

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