C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022429 Dmc1 10090 - 15:79561500-79605084 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023065 Dmc1-201 79561500-79605084 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023065
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023065 0.106±0.05 0.252±0.27 0.219±0.07 0.324±0.18 0.112±0.05 0.078±0.03 0.064±0.03 0.066±0.00 0.161±0.19 0.125±0.05 0.018±0.01 0.234±0.13 0.098±0.06 3.309±0.46

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MM CIL_0008MM_0002 VISTA 15:79023554-79624112
CIL_0005DK CIL_0005DK_0002 CGP 15:79527707-79605084
CIL_0005DL CIL_0005DL_0002 CGP 15:79561500-79658956

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000150 ISS recombinase activity
GO:0000781 IDA chromosome, telomeric region
GO:0000794 IDA condensed nuclear chromosome
GO:0001541 IMP ovarian follicle development
GO:0001556 IMP oocyte maturation
GO:0003690 ISS double-stranded DNA binding
GO:0003697 ISS single-stranded DNA binding
GO:0005515 IEA protein binding
GO:0005524 ISS ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005694 IDA chromosome
GO:0006200 IEA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0007129 IMP synapsis
GO:0007131 IEA reciprocal meiotic recombination
GO:0007141 IMP male meiosis I
GO:0007276 IMP gamete generation
GO:0007283 IMP spermatogenesis
GO:0007286 IMP spermatid development
GO:0008094 IEA DNA-dependent ATPase activity
GO:0016887 ISS ATPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055883 dmc1 DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) protein_coding Danio_rerio
ENSG00000100206 DMC1 DNA meiotic recombinase 1 protein_coding Homo_sapiens

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