C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022449 Adamts20 10090 - 15:94270163-94465418 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035342 Adamts20-001 94270163-94404258 protein_coding
  ENSMUST00000128797 Adamts20-004 94394734-94465418 processed_transcript
  ENSMUST00000129195 Adamts20-003 94351432-94404350 retained_intron
  ENSMUST00000155907 Adamts20-002 94320334-94404258 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035342ENSMUST00000128797ENSMUST00000129195ENSMUST00000155907
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035342 0.131±0.00 0.074±0.02 N/A N/A 0.139±0.04 0.034±0.00 0.035±0.02 0.018±0.01 N/A 0.052±0.00 0.365±0.18 0.112±0.10 0.017±0.01 0.286±0.09
ENSMUST00000128797 N/A 0.334±0.09 N/A N/A N/A N/A N/A N/A N/A 0.447±0.00 N/A 0.297±0.00 N/A N/A
ENSMUST00000129195 0.253±0.00 0.244±0.14 0.223±0.00 N/A 0.335±0.06 0.154±0.08 N/A 0.029±0.01 0.038±0.02 0.174±0.00 N/A 0.138±0.10 0.055±0.04 0.480±0.00
ENSMUST00000155907 0.113±0.09 0.114±0.02 0.119±0.00 0.945±0.46 0.294±0.10 0.151±0.09 0.024±0.01 0.054±0.02 0.041±0.03 N/A N/A 0.117±0.07 0.022±0.02 0.118±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006R4 CIL_0006R4_0002 CGP 15:93499114-94465418
CIL_0006R3 CIL_0006R3_0002 CGP 15:94270163-94543547

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004175 IDA endopeptidase activity
GO:0004222 IDA metalloendopeptidase activity
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0006508 IDA proteolysis
GO:0008270 IEA zinc ion binding
GO:0009967 IMP positive regulation of signal transduction
GO:0030198 IDA extracellular matrix organization
GO:0043066 IMP negative regulation of apoptotic process
GO:0045636 IGI positive regulation of melanocyte differentiation
GO:0048070 IMP regulation of developmental pigmentation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074281 ADAM metallopeptidase with thrombospondin type 1 motif, 20 protein_coding Danio_rerio
ENSG00000173157 ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 protein_coding Homo_sapiens

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