C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: class II transactivator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022504 Ciita 10090 + 16:10488178-10527564 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023147 Ciita-201 10488178-10527564 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBreastColonKidneyLungMuscleOvaryPlacentaENSMUST00000023147
Transcript ID Adipose Bladder Breast Colon Kidney Lung Muscle Ovary Placenta
ENSMUST00000023147 2.954±0.00 1.462±0.20 13.902±7.62 2.775±0.17 1.260±0.36 4.221±1.34 1.474±0.00 1.861±0.38 0.241±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000750 CIL_000750_0002 CGP 16:10420557-10527564
CIL_000751 CIL_000751_0002 CGP 16:10488178-10543054

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0006351 IEA transcription, DNA-templated
GO:0006954 IEA inflammatory response
GO:0007568 IEA aging
GO:0009986 IEA cell surface
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016605 ISS PML body
GO:0016746 IEA transferase activity, transferring acyl groups
GO:0032403 ISS protein complex binding
GO:0034341 IDA response to interferon-gamma
GO:0045348 IEA positive regulation of MHC class II biosynthetic process
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046677 ISO response to antibiotic
GO:0071257 IEA cellular response to electrical stimulus
GO:0071346 IEA cellular response to interferon-gamma
GO:0071360 IEA cellular response to exogenous dsRNA

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090851 ciita class II, major histocompatibility complex, transactivator protein_coding Danio_rerio
ENSG00000179583 CIITA class II, major histocompatibility complex, transactivator protein_coding Homo_sapiens

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