C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mahogunin, ring finger 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022517 Mgrn1 10090 + 16:4886100-4938296 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023159 Mgrn1-201 4886100-4938296 protein_coding
  ENSMUST00000070658 Mgrn1-202 4886100-4938296 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023159ENSMUST00000070658
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023159 7.965±0.77 11.087±2.34 4.294±0.10 6.442±0.47 8.457±0.94 10.124±2.53 10.002±1.87 11.906±1.45 2.949±1.37 6.966±1.23 2.501±0.53 10.567±4.38 3.468±0.53 1.796±0.34
ENSMUST00000070658 42.674±0.63 49.440±3.35 34.029±6.25 41.441±2.66 40.060±11.33 50.105±3.78 71.325±9.93 57.379±5.12 16.296±4.74 42.373±2.36 13.268±1.51 50.559±18.72 18.899±5.63 8.757±3.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007IF CIL_0007IF_0003 CGP 16:4874778-4938296
CIL_00004Z CIL_00004Z_0002 CGP 16:4886100-4941020

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005886 IEA plasma membrane
GO:0008270 IEA zinc ion binding
GO:0016874 IEA ligase activity
GO:0043951 ISS negative regulation of cAMP-mediated signaling
GO:0045744 ISS negative regulation of G-protein coupled receptor protein signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004796 mgrn1b mahogunin, ring finger 1b protein_coding Danio_rerio
ENSDARG00000036451 mgrn1a mahogunin, ring finger 1a protein_coding Danio_rerio
ENSG00000102858 MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase protein_coding Homo_sapiens

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