C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mahogunin ring finger 1, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102858 MGRN1 9606 + 16:4616493-4690974 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262370 MGRN1-001 4624790-4690974 protein_coding
  ENST00000399577 MGRN1-004 4624868-4690972 protein_coding
  ENST00000415496 MGRN1-201 4624824-4690974 protein_coding
  ENST00000536343 MGRN1-002 4624842-4688809 nonsense_mediated_decay
  ENST00000585676 MGRN1-013 4681348-4683872 retained_intron
  ENST00000586183 MGRN1-006 4624961-4689039 protein_coding
  ENST00000587145 MGRN1-008 4664069-4673622 processed_transcript
  ENST00000587747 MGRN1-003 4624846-4688843 protein_coding
  ENST00000588015 MGRN1-014 4668297-4677326 processed_transcript
  ENST00000588111 MGRN1-012 4680428-4682907 processed_transcript
  ENST00000588994 MGRN1-005 4624961-4688908 protein_coding
  ENST00000590457 MGRN1-009 4664416-4673522 retained_intron
  ENST00000590790 MGRN1-017 4650387-4680067 protein_coding
  ENST00000591673 MGRN1-010 4669121-4681580 processed_transcript
  ENST00000591895 MGRN1-007 4616493-4657363 protein_coding
  ENST00000592256 MGRN1-011 4680173-4683932 processed_transcript
  ENST00000593224 MGRN1-019 4650400-4673554 protein_coding
  ENST00000615397 MGRN1-020 4649080-4651106 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262370ENST00000399577ENST00000415496ENST00000586183ENST00000588994ENST00000590457ENST00000590790ENST00000591673ENST00000591895
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262370 25.184±0.00 19.643±0.00 N/A 5.507±3.50 18.632±0.00 4.563±0.00 7.065±0.00 6.330±3.97 5.351±3.27 6.911±5.82 12.487±12.16 26.288±12.65 17.194±6.41 12.141±2.07
ENST00000399577 N/A N/A N/A 0.409±0.00 0.878±0.00 0.985±0.00 0.195±0.00 N/A N/A N/A 0.360±0.00 3.017±2.45 N/A N/A
ENST00000415496 N/A N/A N/A 2.814±0.00 N/A N/A N/A N/A N/A 0.428±0.00 N/A 2.541±0.00 N/A 2.070±0.00
ENST00000586183 N/A N/A N/A N/A N/A N/A 0.321±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000588994 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.097±0.00 0.901±0.00 N/A N/A N/A
ENST00000590457 N/A N/A N/A 7.525±0.00 4.747±0.00 6.530±0.00 N/A 12.097±0.00 N/A 7.164±0.00 N/A N/A N/A N/A
ENST00000590790 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.854±0.00 10.157±7.85 N/A N/A
ENST00000591673 N/A N/A 5.416±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000591895 N/A N/A N/A N/A N/A 6.374±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007IF CIL_0007IF_0002 CGP 16:4608883-4690974
CIL_00004Z CIL_00004Z_0001 CGP 16:4616493-4695859

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IEA protein polyubiquitination
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005769 IDA early endosome
GO:0005886 IEA plasma membrane
GO:0006513 IMP protein monoubiquitination
GO:0008152 IEA metabolic process
GO:0008270 IEA zinc ion binding
GO:0008333 IMP endosome to lysosome transport
GO:0016020 IDA membrane
GO:0016874 IEA ligase activity
GO:0043951 IDA negative regulation of cAMP-mediated signaling
GO:0045744 IDA negative regulation of G-protein coupled receptor protein signaling pathway
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004796 mgrn1b mahogunin, ring finger 1b protein_coding Danio_rerio
ENSDARG00000036451 mgrn1a mahogunin, ring finger 1a protein_coding Danio_rerio
ENSMUSG00000022517 Mgrn1 mahogunin, ring finger 1 protein_coding Mus_musculus

Loading