C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thrombopoietin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022847 Thpo 10090 - 16:20725158-20734511 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076422 Thpo-002 20725158-20730627 protein_coding
  ENSMUST00000115437 Thpo-001 20725158-20734511 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076422ENSMUST00000115437
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076422 2.286±0.27 6.642±0.75 2.617±0.36 2.488±0.66 0.326±0.00 5.490±1.05 6.261±3.74 0.629±0.17 2.613±0.50 0.917±0.05 1.590±1.09 N/A
ENSMUST00000115437 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.221±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00056Y CIL_00056Y_0002 CGP 16:20717665-20734511
CIL_00056V CIL_00056V_0002 CGP 16:20725158-20742384

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0005125 IEA cytokine activity
GO:0005179 IEA hormone activity
GO:0005615 IEA extracellular space
GO:0008283 IEA cell proliferation
GO:0030099 IDA myeloid cell differentiation
GO:0038163 IDA thrombopoietin-mediated signaling pathway
GO:0045654 IDA positive regulation of megakaryocyte differentiation
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000090534 THPO thrombopoietin protein_coding Homo_sapiens

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