C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rac GTPase-activating protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023015 Racgap1 10090 - 15:99620496-99651656 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023756 Racgap1-002 99620497-99651656 protein_coding
  ENSMUST00000109581 Racgap1-012 99639799-99651643 protein_coding
  ENSMUST00000164983 Racgap1-009 99636155-99651612 nonsense_mediated_decay
  ENSMUST00000165730 Racgap1-010 99634293-99651569 nonsense_mediated_decay
  ENSMUST00000165745 Racgap1-014 99626100-99632804 retained_intron
  ENSMUST00000168065 Racgap1-004 99628618-99639817 nonsense_mediated_decay
  ENSMUST00000168834 Racgap1-008 99637459-99651582 retained_intron
  ENSMUST00000168976 Racgap1-006 99632159-99634774 retained_intron
  ENSMUST00000169700 Racgap1-013 99626380-99651589 processed_transcript
  ENSMUST00000169810 Racgap1-011 99632143-99651652 protein_coding
  ENSMUST00000170369 Racgap1-003 99628558-99651582 retained_intron
  ENSMUST00000171017 Racgap1-007 99628664-99638268 retained_intron
  ENSMUST00000171702 Racgap1-001 99620496-99651643 protein_coding
  ENSMUST00000171908 Racgap1-005 99637673-99651612 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023756ENSMUST00000109581ENSMUST00000165745ENSMUST00000168065ENSMUST00000169810ENSMUST00000170369ENSMUST00000171017ENSMUST00000171702
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023756 1.236±0.44 1.506±0.70 2.213±0.19 18.161±11.85 1.838±0.95 2.322±0.32 0.351±0.23 0.592±0.31 20.245±21.56 1.368±0.10 0.435±0.28 6.481±2.60 12.922±9.40 7.492±1.53
ENSMUST00000109581 N/A 3.227±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000165745 N/A 0.970±0.00 N/A N/A N/A N/A N/A 0.716±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000168065 N/A N/A N/A N/A N/A N/A N/A N/A 0.248±0.11 N/A N/A N/A N/A N/A
ENSMUST00000169810 N/A N/A N/A 7.402±0.00 N/A N/A N/A N/A N/A N/A 0.173±0.00 32.567±0.00 50.643±46.42 48.485±0.00
ENSMUST00000170369 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.047±0.01 N/A N/A N/A
ENSMUST00000171017 N/A N/A N/A 1.400±0.00 N/A N/A N/A N/A 0.103±0.00 N/A N/A 5.608±0.00 0.956±0.00 N/A
ENSMUST00000171702 1.563±0.93 1.944±0.11 0.356±0.00 5.467±0.00 1.115±0.63 4.444±1.02 0.375±0.11 0.703±0.35 0.149±0.00 1.184±0.29 0.210±0.00 5.743±2.33 4.117±0.25 7.409±1.65

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PE CIL_0008PE_0002 VISTA 15:99507076-100109694
CIL_0008CC CIL_0008CC_0002 VISTA 15:99507743-100109214
CIL_00071X CIL_00071X_0002 CGP 15:99601400-99651656
CIL_00071Y CIL_00071Y_0002 CGP 15:99620496-99701127

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000281 ISS mitotic cytokinesis
GO:0000915 ISS actomyosin contractile ring assembly
GO:0005096 ISS GTPase activator activity
GO:0005515 IEA protein binding
GO:0005547 ISS phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 ISS nucleus
GO:0007108 ISS cytokinesis, initiation of separation
GO:0007283 ISS spermatogenesis
GO:0007405 IEP neuroblast proliferation
GO:0008017 ISS microtubule binding
GO:0008272 IEA sulfate transport
GO:0009790 IMP embryo development
GO:0019901 IEA protein kinase binding
GO:0030496 ISS midbody
GO:0031234 ISS extrinsic component of cytoplasmic side of plasma membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0032154 ISS cleavage furrow
GO:0032467 ISS positive regulation of cytokinesis
GO:0035556 IEA intracellular signal transduction
GO:0043014 ISS alpha-tubulin binding
GO:0043015 ISS gamma-tubulin binding
GO:0043547 ISS positive regulation of GTPase activity
GO:0046872 IEA metal ion binding
GO:0048487 ISS beta-tubulin binding
GO:0051233 ISS spindle midzone
GO:0051256 ISS spindle midzone assembly involved in mitosis
GO:0051988 ISS regulation of attachment of spindle microtubules to kinetochore
GO:0070062 IEA extracellular vesicular exosome
GO:0072686 ISS mitotic spindle
GO:0097149 ISS centralspindlin complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015460 racgap1 Rac GTPase-activating protein 1 protein_coding Danio_rerio
ENSG00000161800 RACGAP1 Rac GTPase activating protein 1 protein_coding Homo_sapiens

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