C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rac GTPase activating protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000161800 RACGAP1 9606 - 12:49976923-50033136 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312377 RACGAP1-001 49989162-50025461 protein_coding
  ENST00000427314 RACGAP1-004 49989162-50025438 protein_coding
  ENST00000454520 RACGAP1-005 49989164-50025400 protein_coding
  ENST00000546595 RACGAP1-011 50001172-50025416 protein_coding
  ENST00000546723 RACGAP1-030 50004265-50025436 protein_coding
  ENST00000546764 RACGAP1-008 50005264-50025483 protein_coding
  ENST00000546786 RACGAP1-019 50001171-50025463 protein_coding
  ENST00000547061 RACGAP1-015 49997069-50002691 processed_transcript
  ENST00000547905 RACGAP1-003 49990268-50025494 protein_coding
  ENST00000548158 RACGAP1-016 49999310-50004271 retained_intron
  ENST00000548247 RACGAP1-014 50005256-50033136 protein_coding
  ENST00000548320 RACGAP1-013 49997131-50025493 protein_coding
  ENST00000548598 RACGAP1-031 49997160-50025461 nonsense_mediated_decay
  ENST00000548644 RACGAP1-009 50004234-50025451 protein_coding
  ENST00000548824 RACGAP1-026 50002272-50025434 protein_coding
  ENST00000548961 RACGAP1-017 49976923-49992358 protein_coding
  ENST00000549342 RACGAP1-018 49992079-49999736 protein_coding
  ENST00000549777 RACGAP1-010 50005294-50025435 protein_coding
  ENST00000550149 RACGAP1-021 49999675-50025477 protein_coding
  ENST00000550651 RACGAP1-007 50005347-50025494 protein_coding
  ENST00000551016 RACGAP1-002 49989979-50016720 protein_coding
  ENST00000551145 RACGAP1-012 50002248-50025518 protein_coding
  ENST00000551260 RACGAP1-029 50004234-50025435 nonsense_mediated_decay
  ENST00000551876 RACGAP1-006 50005291-50017084 protein_coding
  ENST00000552004 RACGAP1-023 50005358-50025488 protein_coding
  ENST00000552157 RACGAP1-020 50005256-50025443 protein_coding
  ENST00000552310 RACGAP1-024 49999139-50025448 protein_coding
  ENST00000552921 RACGAP1-028 50004278-50025557 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000312377ENST00000427314ENST00000454520ENST00000548320ENST00000548824ENST00000549342ENST00000551016ENST00000551876ENST00000552157
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000312377 1.272±0.00 0.370±0.00 2.270±0.00 1.209±0.91 1.366±0.00 0.607±0.28 N/A 0.735±0.00 1.091±0.00 N/A 7.323±6.99 4.307±2.04 22.777±8.78
ENST00000427314 N/A N/A 0.317±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000454520 0.429±0.00 N/A N/A 0.644±0.00 3.707±0.00 N/A N/A N/A N/A N/A 6.524±0.00 1.960±1.14 N/A
ENST00000548320 N/A N/A N/A N/A N/A N/A 0.709±0.00 N/A N/A N/A N/A N/A N/A
ENST00000548824 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.484±0.00 N/A N/A
ENST00000549342 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.439±0.00 N/A N/A N/A
ENST00000551016 N/A N/A N/A N/A 0.479±0.00 N/A N/A N/A N/A 0.722±0.00 N/A 2.280±0.00 N/A
ENST00000551876 N/A N/A N/A N/A N/A N/A N/A 2.281±0.00 N/A N/A N/A N/A N/A
ENST00000552157 N/A N/A N/A N/A N/A 0.596±0.00 1.426±0.00 1.823±0.00 N/A 2.847±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PE CIL_0008PE_0001 VISTA 12:49905565-50507504
CIL_0008CC CIL_0008CC_0001 VISTA 12:49906068-50507455
CIL_000720 CIL_000720_0001 CGP 12:49961870-49977139
CIL_00071X CIL_00071X_0001 CGP 12:49967194-50033136
CIL_00071Y CIL_00071Y_0001 CGP 12:49976923-50083611

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000281 IDA mitotic cytokinesis
GO:0000915 IMP actomyosin contractile ring assembly
GO:0005096 IDA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005547 IDA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0005874 IEA microtubule
GO:0007018 TAS microtubule-based movement
GO:0007108 IMP cytokinesis, initiation of separation
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007283 IEP spermatogenesis
GO:0007405 ISS neuroblast proliferation
GO:0007596 TAS blood coagulation
GO:0008017 IDA microtubule binding
GO:0008272 IDA sulfate transport
GO:0009790 ISS embryo development
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 IPI protein kinase binding
GO:0030496 IDA midbody
GO:0031234 IDA extrinsic component of cytoplasmic side of plasma membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0032154 IDA cleavage furrow
GO:0032467 IMP positive regulation of cytokinesis
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043014 IDA alpha-tubulin binding
GO:0043015 IDA gamma-tubulin binding
GO:0043547 IEA positive regulation of GTPase activity
GO:0046872 IEA metal ion binding
GO:0048487 IDA beta-tubulin binding
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0051233 IDA spindle midzone
GO:0051256 IDA spindle midzone assembly involved in mitosis
GO:0051988 IMP regulation of attachment of spindle microtubules to kinetochore
GO:0070062 IDA extracellular vesicular exosome
GO:0072686 IMP mitotic spindle
GO:0097149 IDA centralspindlin complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015460 racgap1 Rac GTPase-activating protein 1 protein_coding Danio_rerio
ENSMUSG00000023015 Racgap1 Rac GTPase-activating protein 1 protein_coding Mus_musculus

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