C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sterol O-acyltransferase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023045 Soat2 10090 + 15:102150526-102163474 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023806 Soat2-001 102150526-102163474 protein_coding
  ENSMUST00000160465 Soat2-002 102151116-102163132 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023806ENSMUST00000160465
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023806 0.224±0.04 0.468±0.09 0.491±0.00 0.068±0.03 0.201±0.03 0.400±0.25 0.057±0.00 0.313±0.15 27.838±7.29 0.352±0.05 0.053±0.02 0.900±0.48 14.566±12.98 0.060±0.02
ENSMUST00000160465 N/A N/A N/A N/A 0.199±0.06 0.227±0.05 0.050±0.02 0.149±0.00 N/A N/A 0.049±0.00 N/A 0.519±0.00 0.015±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006TD CIL_0006TD_0002 CGP 15:102144362-102163474
CIL_0006TC CIL_0006TC_0002 CGP 15:102150526-102189043

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000062 IEA fatty-acyl-CoA binding
GO:0004772 IDA sterol O-acyltransferase activity
GO:0005783 IEA endoplasmic reticulum
GO:0005789 IEA endoplasmic reticulum membrane
GO:0005903 IEA brush border
GO:0008203 IDA cholesterol metabolic process
GO:0015485 IEA cholesterol binding
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0033344 IEA cholesterol efflux
GO:0034379 IEA very-low-density lipoprotein particle assembly
GO:0034435 IEA cholesterol esterification
GO:0034736 IEA cholesterol O-acyltransferase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059824 soat2 sterol O-acyltransferase 2 protein_coding Danio_rerio
ENSG00000167780 SOAT2 sterol O-acyltransferase 2 protein_coding Homo_sapiens

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