C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein arginine N-methyltransferase 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023110 Prmt5 10090 - 14:54507187-54517525 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023873 Prmt5-001 54507187-54517525 protein_coding
  ENSMUST00000132227 Prmt5-003 54511206-54517435 nonsense_mediated_decay
  ENSMUST00000132801 Prmt5-005 54516151-54517361 processed_transcript
  ENSMUST00000133552 Prmt5-002 54513937-54517470 retained_intron
  ENSMUST00000138367 Prmt5-006 54514595-54515658 processed_transcript
  ENSMUST00000139964 Prmt5-007 54511001-54513456 protein_coding
  ENSMUST00000147214 Prmt5-004 54513373-54517393 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023873ENSMUST00000132801ENSMUST00000147214
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023873 18.744±3.51 14.786±4.08 15.568±0.94 21.608±14.62 11.997±3.32 10.366±1.66 10.317±2.17 14.431±1.29 12.426±9.33 9.947±1.29 13.834±2.11 13.633±6.65 18.988±12.60 8.537±1.30
ENSMUST00000132801 N/A 23.936±0.25 N/A N/A N/A 15.903±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000147214 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 20.443±7.93 1.842±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006WJ CIL_0006WJ_0002 CGP 14:54507187-54554361

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000387 ISS spliceosomal snRNP assembly
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0003682 IMP chromatin binding
GO:0003714 IMP transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 ISS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0008168 ISO methyltransferase activity
GO:0008469 IBA histone-arginine N-methyltransferase activity
GO:0018216 ISS peptidyl-arginine methylation
GO:0019918 IBA peptidyl-arginine methylation, to symmetrical-dimethyl arginine
GO:0032922 IMP circadian regulation of gene expression
GO:0034709 ISS methylosome
GO:0034969 IBA histone arginine methylation
GO:0035243 ISS protein-arginine omega-N symmetric methyltransferase activity
GO:0035246 ISO peptidyl-arginine N-methylation
GO:0042118 IEA endothelial cell activation
GO:0043021 IEA ribonucleoprotein complex binding
GO:0043234 IEA protein complex
GO:0043985 IMP histone H4-R3 methylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079605 prmt5 protein arginine methyltransferase 5 protein_coding Danio_rerio
ENSG00000100462 PRMT5 protein arginine methyltransferase 5 protein_coding Homo_sapiens

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