C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATP-binding cassette, sub-family G (WHITE), member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000024829 Abcg1-001 ENSMUSG00000024030 10090 + 17:31057698-31115777 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024829
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024829 6.661±1.44 6.894±0.98 3.487±0.46 3.727±0.48 17.644±7.50 4.715±0.22 1.621±0.43 4.246±0.95 2.001±0.81 43.551±5.67 0.508±0.38 6.755±2.24 7.071±8.42 0.265±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036J CIL_00036J_0002 CGP 17:30954679-31115777
CIL_0008QJ CIL_0008QJ_0002 VISTA 17:31053737-31653776
CIL_0004VV CIL_0004VV_0002 CGP 17:31057698-31129646

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005548 IEA phospholipid transporter activity
GO:0005739 IEA mitochondrion
GO:0005768 IDA endosome
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0008203 IEA cholesterol metabolic process
GO:0009897 IDA external side of plasma membrane
GO:0010033 IEA response to organic substance
GO:0010745 IC negative regulation of macrophage derived foam cell differentiation
GO:0010872 IMP regulation of cholesterol esterification
GO:0010875 IDA positive regulation of cholesterol efflux
GO:0010888 IMP negative regulation of lipid storage
GO:0016021 IEA integral component of membrane
GO:0017127 IEA cholesterol transporter activity
GO:0019534 IEA toxin transporter activity
GO:0030301 IDA cholesterol transport
GO:0032367 IEA intracellular cholesterol transport
GO:0033344 IMP cholesterol efflux
GO:0033700 IEA phospholipid efflux
GO:0033993 IEA response to lipid
GO:0034041 IEA sterol-transporting ATPase activity
GO:0034374 IMP low-density lipoprotein particle remodeling
GO:0034375 IMP high-density lipoprotein particle remodeling
GO:0034436 IEA glycoprotein transport
GO:0034437 IEA glycoprotein transporter activity
GO:0042632 IEA cholesterol homeostasis
GO:0042803 IEA protein homodimerization activity
GO:0042987 IEA amyloid precursor protein catabolic process
GO:0043531 IEA ADP binding
GO:0043691 IMP reverse cholesterol transport
GO:0045542 IMP positive regulation of cholesterol biosynthetic process
GO:0046982 IEA protein heterodimerization activity
GO:0055037 IDA recycling endosome
GO:0055091 IEA phospholipid homeostasis
GO:0055099 IDA response to high density lipoprotein particle
GO:1901998 IEA toxin transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000092809 abcg1-001 protein_coding Danio_rerio 0 1229
ENST00000343687 ABCG1-005 protein_coding Homo_sapiens 0 2263
ENST00000347800 ABCG1-004 protein_coding Homo_sapiens 0 2263
ENST00000361802 ABCG1-006 protein_coding Homo_sapiens 0 1286
ENST00000398437 ABCG1-008 protein_coding Homo_sapiens 0 1103
ENST00000398449 ABCG1-001 protein_coding Homo_sapiens 0 2383
ENST00000398457 ABCG1-002 protein_coding Homo_sapiens 0 2265
ENST00000450121 ABCG1-010 protein_coding Homo_sapiens 0 634
ENST00000462050 ABCG1-003 processed_transcript Homo_sapiens 0 2265
ENST00000472587 ABCG1-007 retained_intron Homo_sapiens 0 1103
ENST00000496783 ABCG1-009 retained_intron Homo_sapiens 0 828
ENST00000533694 ABCG4-004 retained_intron Homo_sapiens 0 468
ENST00000534402 ABCG4-006 retained_intron Homo_sapiens 4e-28 130
ENST00000615496 ABCG4-002 protein_coding Homo_sapiens 0 523
ENST00000619701 ABCG4-001 protein_coding Homo_sapiens 0 523
ENST00000622721 ABCG4-003 protein_coding Homo_sapiens 0 523

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