C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: son of sevenless homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024241 Sos1 10090 - 17:80393752-80480453 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000068714 Sos1-201 80393752-80480453 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000068714
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000068714 2.178±0.63 1.628±0.19 0.912±0.27 5.305±3.33 1.490±0.47 2.040±0.32 1.050±0.34 2.724±0.25 1.753±0.57 2.010±0.38 2.317±0.23 2.362±1.30 8.212±1.68 1.500±0.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000675 CIL_000675_0002 CGP 17:80393752-80563834

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005088 IMP Ras guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0007264 IMP small GTPase mediated signal transduction
GO:0007265 IEA Ras protein signal transduction
GO:0014069 IEA postsynaptic density
GO:0017124 IEA SH3 domain binding
GO:0032320 IMP positive regulation of Ras GTPase activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043025 IEA neuronal cell body
GO:0045742 IEA positive regulation of epidermal growth factor receptor signaling pathway
GO:0046982 IEA protein heterodimerization activity
GO:0048011 IEA neurotrophin TRK receptor signaling pathway
GO:0051057 IEA positive regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042468 sos1 son of sevenless homolog 1 (Drosophila) protein_coding Danio_rerio
ENSG00000115904 SOS1 son of sevenless homolog 1 (Drosophila) protein_coding Homo_sapiens

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