C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: son of sevenless homolog 1 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000068714 Sos1-201 ENSMUSG00000024241 10090 - 17:80393752-80480453 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000068714
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000068714 2.178±0.63 1.628±0.19 0.912±0.27 5.305±3.33 1.490±0.47 2.040±0.32 1.050±0.34 2.724±0.25 1.753±0.57 2.010±0.38 2.317±0.23 2.362±1.30 8.212±1.68 1.500±0.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000675 CIL_000675_0002 CGP 17:80393752-80563834

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005088 IMP Ras guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0007264 IMP small GTPase mediated signal transduction
GO:0007265 IEA Ras protein signal transduction
GO:0014069 IEA postsynaptic density
GO:0017124 IEA SH3 domain binding
GO:0032320 IMP positive regulation of Ras GTPase activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043025 IEA neuronal cell body
GO:0045742 IEA positive regulation of epidermal growth factor receptor signaling pathway
GO:0046982 IEA protein heterodimerization activity
GO:0048011 IEA neurotrophin TRK receptor signaling pathway
GO:0051057 IEA positive regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000062269 sos1-201 protein_coding Danio_rerio 0 510
ENSDART00000125719 protein_coding Danio_rerio 0 433
ENST00000395038 SOS1-003 protein_coding Homo_sapiens 0 5541
ENST00000402219 SOS1-201 protein_coding Homo_sapiens 0 4542
ENST00000426016 SOS1-001 protein_coding Homo_sapiens 0 4542
ENST00000451331 SOS1-004 protein_coding Homo_sapiens 0 595
ENST00000461545 SOS1-005 retained_intron Homo_sapiens 0 486
ENST00000469581 SOS1-007 retained_intron Homo_sapiens 0 534
ENST00000472480 SOS1-008 processed_transcript Homo_sapiens 0 508
ENST00000474390 SOS1-006 retained_intron Homo_sapiens 0 521

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