C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU domain, class 5, transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024406 Pou5f1 10090 + 17:35506018-35510772 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025271 Pou5f1-001 35506018-35510772 protein_coding
  ENSMUST00000172651 Pou5f1-003 35508805-35510134 protein_coding
  ENSMUST00000173256 Pou5f1-004 35508817-35510134 protein_coding
  ENSMUST00000173805 Pou5f1-005 35508807-35510134 protein_coding
  ENSMUST00000173934 Pou5f1-002 35507482-35510134 protein_coding
  ENSMUST00000174782 Pou5f1-006 35508821-35510134 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLiverOvaryPlacentaTestisENSMUST00000025271ENSMUST00000172651ENSMUST00000173934ENSMUST00000174782
Transcript ID Brain Heart Liver Ovary Placenta Testis
ENSMUST00000025271 0.011±0.00 0.022±0.00 0.008±0.00 1.704±0.48 0.021±0.01 3.473±1.03
ENSMUST00000172651 N/A N/A N/A 3.093±0.00 0.161±0.14 N/A
ENSMUST00000173934 N/A N/A N/A N/A 0.008±0.00 N/A
ENSMUST00000174782 N/A N/A 0.016±0.00 N/A 0.019±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090O CIL_00090O_0002 VISTA 17:35419853-36021785

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001105 IEA RNA polymerase II transcription coactivator activity
GO:0001710 IDA mesodermal cell fate commitment
GO:0001711 IDA endodermal cell fate commitment
GO:0001712 IDA ectodermal cell fate commitment
GO:0001714 ISO endodermal cell fate specification
GO:0001824 IEP blastocyst development
GO:0001829 IGI trophectodermal cell differentiation
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0008134 IPI transcription factor binding
GO:0009786 IEP regulation of asymmetric cell division
GO:0010033 IDA response to organic substance
GO:0017053 IDA transcriptional repressor complex
GO:0019827 IMP stem cell maintenance
GO:0030718 IMP germ-line stem cell maintenance
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032526 IDA response to retinoic acid
GO:0034097 IEA response to cytokine
GO:0042789 IDA mRNA transcription from RNA polymerase II promoter
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IDA nuclear transcription factor complex
GO:0045165 IMP cell fate commitment
GO:0045596 IGI negative regulation of cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI:IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045955 IDA negative regulation of calcium ion-dependent exocytosis
GO:0046982 IDA protein heterodimerization activity
GO:0048863 IDA stem cell differentiation
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0070974 IEA POU domain binding
GO:0071837 IEA HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044774 pou5f3 POU domain, class 5, transcription factor 3 protein_coding Danio_rerio
ENSG00000204531 POU5F1 POU class 5 homeobox 1 protein_coding Homo_sapiens
ENSG00000212993 POU5F1B POU class 5 homeobox 1B protein_coding Homo_sapiens

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