C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aquaporin 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024411 Aqp4 10090 - 18:15389394-15403684 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000079081 Aqp4-201 15389394-15403684 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000079081
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000079081 0.081±0.01 0.033±0.00 0.006±0.00 2.198±2.84 2.434±1.93 45.776±10.25 1.411±0.16 8.520±1.54 0.334±0.37 1.903±0.96 4.289±1.16 0.301±0.15 0.027±0.01 0.005±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006EQ CIL_0006EQ_0002 CGP 18:14968685-15403684
CIL_0006EP CIL_0006EP_0002 CGP 18:15389394-15760157

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005911 IDA cell-cell junction
GO:0006833 IMP water transport
GO:0007565 IEA female pregnancy
GO:0007605 IMP sensory perception of sound
GO:0009314 IEA response to radiation
GO:0009897 IEA external side of plasma membrane
GO:0015250 IDA water channel activity
GO:0015288 IEA porin activity
GO:0015670 IEA carbon dioxide transport
GO:0016021 NAS integral component of membrane
GO:0016323 IDA basolateral plasma membrane
GO:0030104 IMP water homeostasis
GO:0030315 IEA T-tubule
GO:0042383 IEA sarcolemma
GO:0042538 IEA hyperosmotic salinity response
GO:0043234 IEA protein complex
GO:0050891 IEA multicellular organismal water homeostasis
GO:0051260 IEA protein homooligomerization
GO:0051384 IEA response to glucocorticoid
GO:0055085 IEA transmembrane transport
GO:0070295 IGI renal water absorption
GO:0071346 IEA cellular response to interferon-gamma
GO:0071392 IEA cellular response to estradiol stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010565 aqp4 aquaporin 4 protein_coding Danio_rerio
ENSG00000171885 AQP4 aquaporin 4 protein_coding Homo_sapiens

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