C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aquaporin 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171885 AQP4 9606 - 18:26852038-26865818 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000383168 AQP4-001 26852038-26865818 protein_coding
  ENST00000383170 AQP4-008 26861254-26865771 nonsense_mediated_decay
  ENST00000440832 AQP4-005 26856211-26863190 protein_coding
  ENST00000578776 AQP4-002 26860785-26865707 protein_coding
  ENST00000581374 AQP4-003 26855817-26862848 protein_coding
  ENST00000583022 AQP4-006 26856289-26862176 processed_transcript
  ENST00000584088 AQP4-004 26860691-26862406 retained_intron
  ENST00000622234 AQP4-201 26856211-26865689 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000383168ENST00000578776ENST00000581374ENST00000583022ENST00000622234
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000383168 0.018±0.00 0.039±0.00 111.291±68.53 1.298±0.00 1.262±0.00 0.043±0.00 N/A 20.242±3.53 2.734±2.33 0.297±0.00 0.031±0.03 0.336±0.00
ENST00000578776 N/A 0.120±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000581374 N/A N/A N/A N/A 0.462±0.00 N/A 0.410±0.00 N/A N/A N/A N/A N/A
ENST00000583022 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.273±0.00
ENST00000622234 0.078±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.388±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006EQ CIL_0006EQ_0001 CGP 18:26454910-26865818
CIL_0006EP CIL_0006EP_0001 CGP 18:26852038-27185317

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005215 IEA transporter activity
GO:0005372 TAS water transmembrane transporter activity
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0005911 IEA cell-cell junction
GO:0006810 TAS:IEA transport
GO:0006833 TAS water transport
GO:0007565 IEA female pregnancy
GO:0007605 IEA sensory perception of sound
GO:0009314 IEA response to radiation
GO:0009897 IDA external side of plasma membrane
GO:0015250 EXP water channel activity
GO:0015288 IEA porin activity
GO:0015670 IEA carbon dioxide transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0030104 IEA water homeostasis
GO:0030315 IEA T-tubule
GO:0042383 IEA sarcolemma
GO:0042538 IEA hyperosmotic salinity response
GO:0043234 IEA protein complex
GO:0050891 IEP multicellular organismal water homeostasis
GO:0051260 IEA protein homooligomerization
GO:0051384 IEA response to glucocorticoid
GO:0055085 TAS transmembrane transport
GO:0070295 IEA renal water absorption
GO:0071346 IDA cellular response to interferon-gamma
GO:0071392 IEA cellular response to estradiol stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010565 aqp4 aquaporin 4 protein_coding Danio_rerio
ENSMUSG00000024411 Aqp4 aquaporin 4 protein_coding Mus_musculus

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