C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein geranylgeranyltransferase type I, beta subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024477 Pggt1b 10090 - 18:46239949-46280850 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025354 Pggt1b-201 46239949-46280850 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000025354
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000025354 1.877±0.53 3.359±0.83 2.396±0.97 3.114±1.43 4.843±1.25 0.893±0.17 2.116±0.57 1.312±0.38 5.617±2.33 3.530±1.01 2.987±0.89 1.400±0.53

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004UL CIL_0004UL_0002 CGP 18:46165302-46280850
CIL_0004UK CIL_0004UK_0002 CGP 18:46239949-46311928

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004661 ISS protein geranylgeranyltransferase activity
GO:0004662 ISS CAAX-protein geranylgeranyltransferase activity
GO:0005515 IEA protein binding
GO:0005953 ISS CAAX-protein geranylgeranyltransferase complex
GO:0008144 IEA drug binding
GO:0008270 ISS zinc ion binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0018344 ISS protein geranylgeranylation
GO:0019840 IEA isoprenoid binding
GO:0034097 IEA response to cytokine
GO:0042277 IEA peptide binding
GO:0045787 IEA positive regulation of cell cycle
GO:0051771 IEA negative regulation of nitric-oxide synthase biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058613 pggt1b protein geranylgeranyltransferase type I, beta subunit protein_coding Danio_rerio
ENSG00000164219 PGGT1B protein geranylgeranyltransferase type I, beta subunit protein_coding Homo_sapiens

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