C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein geranylgeranyltransferase type I, beta subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164219 PGGT1B 9606 - 5:115210830-115262872 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296642 PGGT1B-005 115216865-115253176 processed_transcript
  ENST00000379615 PGGT1B-002 115212402-115262851 protein_coding
  ENST00000419445 PGGT1B-001 115210830-115262872 protein_coding
  ENST00000503638 PGGT1B-003 115252831-115262865 retained_intron
  ENST00000514178 PGGT1B-004 115216865-115231784 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379615ENST00000419445ENST00000514178
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379615 N/A N/A 4.252±0.00 N/A N/A N/A N/A 2.628±0.00 2.969±0.00 N/A 3.029±0.00 4.597±0.00 2.604±0.00 N/A
ENST00000419445 3.080±0.00 3.896±0.00 N/A 1.759±0.91 2.054±0.93 2.243±0.00 1.795±0.05 2.360±0.89 2.591±0.00 0.959±0.08 1.495±0.00 3.398±0.94 2.475±0.14 3.201±1.00
ENST00000514178 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.034±0.00 4.571±0.00 4.143±0.00 4.836±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004UL CIL_0004UL_0001 CGP 5:115124762-115262872
CIL_0004UK CIL_0004UK_0001 CGP 5:115210830-115296831

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004661 IDA protein geranylgeranyltransferase activity
GO:0004662 ISS CAAX-protein geranylgeranyltransferase activity
GO:0005515 IEA protein binding
GO:0005953 IDA CAAX-protein geranylgeranyltransferase complex
GO:0008144 IEA drug binding
GO:0008270 ISS zinc ion binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0018344 IDA protein geranylgeranylation
GO:0019840 IEA isoprenoid binding
GO:0034097 IEA response to cytokine
GO:0042277 IEA peptide binding
GO:0045787 IEA positive regulation of cell cycle
GO:0051771 IEA negative regulation of nitric-oxide synthase biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058613 pggt1b protein geranylgeranyltransferase type I, beta subunit protein_coding Danio_rerio
ENSMUSG00000024477 Pggt1b protein geranylgeranyltransferase type I, beta subunit protein_coding Mus_musculus

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