C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025642 Prpf19-001 ENSMUSG00000024735 10090 + 19:10895231-10905532 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025642
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025642 92.065±37.48 168.497±20.75 52.102±9.34 85.283±49.13 88.955±15.19 69.906±15.72 120.548±33.14 57.950±5.48 72.820±17.34 69.159±3.66 86.362±9.63 159.523±72.90 48.120±28.86 26.784±11.17

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000244 ISS spliceosomal tri-snRNP complex assembly
GO:0000398 ISS mRNA splicing, via spliceosome
GO:0000974 ISS Prp19 complex
GO:0001833 IMP inner cell mass cell proliferation
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005662 ISS DNA replication factor A complex
GO:0005681 ISA spliceosomal complex
GO:0005737 IDA cytoplasm
GO:0005811 IDA lipid particle
GO:0005856 IEA cytoskeleton
GO:0006303 ISS double-strand break repair via nonhomologous end joining
GO:0008610 IDA lipid biosynthetic process
GO:0010498 IMP proteasomal protein catabolic process
GO:0016607 ISS nuclear speck
GO:0034613 ISS cellular protein localization
GO:0035861 ISS site of double-strand break
GO:0045665 IDA negative regulation of neuron differentiation
GO:0045666 ISA positive regulation of neuron differentiation
GO:0048026 IMP positive regulation of mRNA splicing, via spliceosome
GO:0048711 IDA positive regulation of astrocyte differentiation
GO:0061630 ISS ubiquitin protein ligase activity
GO:0070534 ISS protein K63-linked ubiquitination
GO:0072422 ISS signal transduction involved in DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000227524 PRPF19-001 protein_coding Homo_sapiens 0 2169
ENST00000535326 PRPF19-007 protein_coding Homo_sapiens 0 363
ENST00000539960 PRPF19-004 retained_intron Homo_sapiens 0 719
ENST00000541371 PRPF19-003 protein_coding Homo_sapiens 0 1007
ENST00000546152 PRPF19-002 protein_coding Homo_sapiens 0 749

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