C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Fas (TNF receptor superfamily member 6)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024778 Fas 10090 + 19:34290659-34327770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025691 Fas-201 34290659-34327770 protein_coding
  ENSMUST00000112472 Fas-202 34290659-34309350 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025691ENSMUST00000112472
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025691 3.642±2.40 0.526±0.23 6.166±0.14 0.137±0.04 2.348±1.55 1.171±0.36 2.622±0.47 2.160±0.55 3.472±2.51 7.655±1.29 1.800±0.63 0.885±0.59 3.274±3.62 0.183±0.13
ENSMUST00000112472 N/A N/A N/A N/A N/A N/A N/A 0.955±0.00 N/A N/A N/A N/A N/A 0.139±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001VG CIL_0001VG_0002 CGP 19:34241090-34327770
CIL_0001IV CIL_0001IV_0002 CGP 19:34290659-34475135

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002377 IMP immunoglobulin production
GO:0003014 IMP renal system process
GO:0004888 IEA transmembrane signaling receptor activity
GO:0005515 IPI protein binding
GO:0005576 IDA extracellular region
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006915 IMP apoptotic process
GO:0006924 IDA activation-induced cell death of T cells
GO:0006925 IDA inflammatory cell apoptotic process
GO:0006927 IDA transformed cell apoptotic process
GO:0007623 IEP circadian rhythm
GO:0008625 IMP extrinsic apoptotic signaling pathway via death domain receptors
GO:0009636 IMP response to toxic substance
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010467 IMP gene expression
GO:0016021 IEA integral component of membrane
GO:0019724 IMP B cell mediated immunity
GO:0019900 IEA kinase binding
GO:0031264 IEA death-inducing signaling complex
GO:0031265 IDA CD95 death-inducing signaling complex
GO:0032464 IDA positive regulation of protein homooligomerization
GO:0042802 IEA identical protein binding
GO:0043029 IMP T cell homeostasis
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0045060 IMP negative thymic T cell selection
GO:0045121 IEA membrane raft
GO:0045619 IMP regulation of lymphocyte differentiation
GO:0045637 IMP regulation of myeloid cell differentiation
GO:0048536 IMP spleen development
GO:0050869 IMP negative regulation of B cell activation
GO:0051260 IDA protein homooligomerization
GO:0051384 IMP response to glucocorticoid
GO:0051402 IMP neuron apoptotic process
GO:0070062 IEA extracellular vesicular exosome
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071285 IMP cellular response to lithium ion
GO:0071455 IEA cellular response to hyperoxia
GO:0090200 IC positive regulation of release of cytochrome c from mitochondria
GO:0097049 IMP motor neuron apoptotic process
GO:0097190 IDA apoptotic signaling pathway
GO:0097191 IMP extrinsic apoptotic signaling pathway
GO:0097192 IMP extrinsic apoptotic signaling pathway in absence of ligand
GO:0097284 IGI hepatocyte apoptotic process
GO:0097527 IGI necroptotic signaling pathway
GO:2001241 IMP positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043586 fas Fas (TNF receptor superfamily, member 6) protein_coding Danio_rerio
ENSG00000026103 FAS Fas cell surface death receptor protein_coding Homo_sapiens

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