C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific demethylase 5C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025332 Kdm5c 10090 + X:152233020-152274535 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000082177 Kdm5c-004 152233272-152273772 protein_coding
  ENSMUST00000112584 Kdm5c-002 152233020-152273768 protein_coding
  ENSMUST00000112588 Kdm5c-001 152233229-152274535 protein_coding
  ENSMUST00000154938 Kdm5c-003 152233254-152246751 retained_intron
  ENSMUST00000155793 Kdm5c-006 152271913-152273396 protein_coding
  ENSMUST00000156114 Kdm5c-005 152269806-152271556 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000082177ENSMUST00000112584ENSMUST00000112588ENSMUST00000156114
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000082177 7.963±1.23 12.448±2.38 2.206±0.02 5.485±2.69 9.988±2.53 12.084±3.76 3.099±1.00 6.900±1.04 5.178±2.28 4.657±0.84 1.558±0.30 16.997±3.09 14.059±7.13 0.723±0.10
ENSMUST00000112584 5.203±2.20 7.038±1.42 2.824±0.44 2.798±0.37 4.491±0.78 8.135±3.44 1.548±0.31 3.190±0.72 4.580±1.25 3.752±0.93 0.816±0.23 6.025±1.11 6.428±1.65 0.686±0.36
ENSMUST00000112588 6.806±2.03 3.588±0.48 7.586±0.38 8.431±4.69 6.121±1.53 5.453±2.17 3.308±0.71 5.596±1.02 4.806±1.71 6.863±0.71 1.604±0.32 8.272±1.30 8.540±2.20 1.253±0.71
ENSMUST00000156114 N/A 23.214±3.55 N/A N/A N/A 19.226±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00062O CIL_00062O_0002 CGP X:152144268-152274535

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032453 IEA histone demethylase activity (H3-K4 specific)
GO:0034720 IEA histone H3-K4 demethylation
GO:0042752 NAS regulation of circadian rhythm
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006124 kdm5c lysine (K)-specific demethylase 5C protein_coding Danio_rerio
ENSG00000126012 KDM5C lysine (K)-specific demethylase 5C protein_coding Homo_sapiens

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