C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine hydroxymethyltransferase 2 (mitochondrial)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000026470 Shmt2-201 ENSMUSG00000025403 10090 - 10:127517123-127522444 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026470
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026470 16.175±3.02 32.375±8.36 21.591±2.74 17.377±11.89 11.875±5.37 12.048±1.72 12.964±1.88 78.756±13.00 73.954±23.77 11.342±2.64 7.699±2.01 24.232±9.30 28.703±17.83 4.003±1.87

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003682 IEA chromatin binding
GO:0004372 IEA glycine hydroxymethyltransferase activity
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005758 IEA mitochondrial intermembrane space
GO:0005759 IEA mitochondrial matrix
GO:0006545 IEA glycine biosynthetic process
GO:0006564 IEA L-serine biosynthetic process
GO:0006730 IEA one-carbon metabolic process
GO:0008284 IEA positive regulation of cell proliferation
GO:0008732 IEA L-allo-threonine aldolase activity
GO:0015630 IEA microtubule cytoskeleton
GO:0016597 IEA amino acid binding
GO:0019264 IEA glycine biosynthetic process from serine
GO:0030170 IEA pyridoxal phosphate binding
GO:0035999 IEA tetrahydrofolate interconversion
GO:0042645 IEA mitochondrial nucleoid
GO:0042802 IEA identical protein binding
GO:0051289 IEA protein homotetramerization
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000328923 SHMT2-001 protein_coding Homo_sapiens 0 1834
ENST00000393825 NDUFA4L2-201 protein_coding Homo_sapiens 0.000006 57
ENST00000414700 SHMT2-005 protein_coding Homo_sapiens 0 1801
ENST00000449049 SHMT2-008 protein_coding Homo_sapiens 0 1797
ENST00000553324 SHMT2-017 retained_intron Homo_sapiens 0 257
ENST00000553474 SHMT2-009 protein_coding Homo_sapiens 0 1801
ENST00000553529 SHMT2-022 protein_coding Homo_sapiens 0 579
ENST00000553837 SHMT2-011 nonsense_mediated_decay Homo_sapiens 0 1092
ENST00000553868 SHMT2-032 retained_intron Homo_sapiens 0 370
ENST00000553949 SHMT2-037 processed_transcript Homo_sapiens 0 324
ENST00000553950 SHMT2-018 retained_intron Homo_sapiens 0 381
ENST00000554310 SHMT2-023 protein_coding Homo_sapiens 0 640
ENST00000554467 SHMT2-002 retained_intron Homo_sapiens 0 390
ENST00000554503 NDUFA4L2-001 protein_coding Homo_sapiens 0.0000005 60
ENST00000554600 SHMT2-034 processed_transcript Homo_sapiens 0 747
ENST00000554604 SHMT2-036 nonsense_mediated_decay Homo_sapiens 0 708
ENST00000554656 SHMT2-026 processed_transcript Homo_sapiens 0 713
ENST00000554975 SHMT2-028 protein_coding Homo_sapiens 0 846
ENST00000555116 SHMT2-010 nonsense_mediated_decay Homo_sapiens 0 1092
ENST00000555213 SHMT2-031 retained_intron Homo_sapiens 0 370
ENST00000555563 SHMT2-035 nonsense_mediated_decay Homo_sapiens 0 394
ENST00000555634 SHMT2-019 protein_coding Homo_sapiens 0 1072
ENST00000555773 SHMT2-027 protein_coding Homo_sapiens 0 593
ENST00000555774 SHMT2-012 nonsense_mediated_decay Homo_sapiens 0 1092
ENST00000556689 SHMT2-033 protein_coding Homo_sapiens 0 747
ENST00000556737 SHMT2-038 protein_coding Homo_sapiens 0 580
ENST00000556798 SHMT2-029 retained_intron Homo_sapiens 0 202
ENST00000556825 SHMT2-004 nonsense_mediated_decay Homo_sapiens 0 1461
ENST00000557269 SHMT2-020 nonsense_mediated_decay Homo_sapiens 0 368
ENST00000557348 SHMT2-006 nonsense_mediated_decay Homo_sapiens 0 1439
ENST00000557427 SHMT2-025 protein_coding Homo_sapiens 0 634
ENST00000557433 SHMT2-013 nonsense_mediated_decay Homo_sapiens 0 1799
ENST00000557487 SHMT2-015 protein_coding Homo_sapiens 0 1053
ENST00000557529 SHMT2-030 protein_coding Homo_sapiens 0 896
ENST00000557703 SHMT2-021 protein_coding Homo_sapiens 0 556
ENST00000557740 SHMT2-016 processed_transcript Homo_sapiens 0 340

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