C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sirtuin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025486 Sirt3 10090 - 7:140863670-140882309 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026559 Sirt3-001 140863670-140882309 protein_coding
  ENSMUST00000106048 Sirt3-002 140863670-140881869 protein_coding
  ENSMUST00000137024 Sirt3-005 140865020-140878147 protein_coding
  ENSMUST00000137710 Sirt3-003 140876434-140881869 protein_coding
  ENSMUST00000147331 Sirt3-004 140869489-140881869 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastHeartKidneyLiverMuscleOvaryTestisENSMUST00000026559ENSMUST00000106048ENSMUST00000147331
Transcript ID Adrenal Bladder Brain Breast Heart Kidney Liver Muscle Ovary Testis
ENSMUST00000026559 N/A N/A N/A N/A N/A N/A N/A N/A N/A 21.100±2.68
ENSMUST00000106048 25.254±2.35 19.529±0.00 34.429±0.00 17.495±3.49 30.122±0.92 47.654±12.35 54.435±14.12 25.065±0.18 22.730±2.89 21.428±1.77
ENSMUST00000147331 N/A N/A N/A N/A N/A N/A 38.005±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006LA CIL_0006LA_0002 CGP 7:140856957-140882309
CIL_0006QN CIL_0006QN_0002 CGP 7:140863670-140898643

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA:ISS mitochondrion
GO:0006476 IDA:ISS protein deacetylation
GO:0007568 IEA aging
GO:0008270 ISS zinc ion binding
GO:0009060 ISS aerobic respiration
GO:0016020 IDA membrane
GO:0019899 IEA enzyme binding
GO:0032041 IDA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0034983 ISS peptidyl-lysine deacetylation
GO:0070403 IEA NAD+ binding
GO:0070932 IDA histone H3 deacetylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035819 sirt3 sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) protein_coding Danio_rerio
ENSG00000142082 SIRT3 sirtuin 3 protein_coding Homo_sapiens

Loading