C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Harvey rat sarcoma virus oncogene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025499 Hras 10090 - 7:141189105-141194005 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026572 Hras-002 141189105-141193960 protein_coding
  ENSMUST00000097957 Hras-001 141190926-141194005 protein_coding
  ENSMUST00000124314 Hras-005 141190927-141192504 processed_transcript
  ENSMUST00000124971 Hras-004 141190930-141193882 nonsense_mediated_decay
  ENSMUST00000128993 Hras-003 141190926-141193994 retained_intron
  ENSMUST00000134008 Hras-006 141190930-141191977 processed_transcript
  ENSMUST00000168550 Hras-201 141189934-141194004 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026572ENSMUST00000097957ENSMUST00000124971ENSMUST00000128993ENSMUST00000134008ENSMUST00000168550
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026572 N/A N/A N/A 4.062±0.00 N/A 3.798±0.44 N/A 2.449±0.27 3.395±0.97 4.284±0.00 N/A 3.554±0.35 2.595±0.59 2.639±0.46
ENSMUST00000097957 22.324±12.77 16.825±5.19 40.773±5.29 50.914±8.86 23.718±6.50 23.935±11.88 17.072±8.15 17.583±7.88 23.527±10.78 11.118±0.00 36.583±5.72 32.548±6.26 27.247±10.75 17.945±1.02
ENSMUST00000124971 N/A 6.223±0.14 N/A 14.867±0.00 7.779±0.00 N/A N/A N/A N/A 10.668±0.00 N/A 4.538±0.00 11.807±0.00 2.177±0.00
ENSMUST00000128993 N/A N/A 6.868±0.00 13.744±0.00 N/A N/A N/A N/A 6.153±0.63 N/A 5.391±0.00 4.823±0.53 5.126±1.30 6.368±0.00
ENSMUST00000134008 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.036±0.00 N/A 19.409±0.00
ENSMUST00000168550 N/A 2.829±0.45 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OR CIL_0003OR_0002 CGP 7:141160328-141194005
CIL_00040A CIL_00040A_0003 CGP 7:141189105-141210055

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0003924 TAS GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IDA GTP binding
GO:0005794 ISS Golgi apparatus
GO:0005886 ISS plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0006897 IDA endocytosis
GO:0006915 IEA apoptotic process
GO:0007050 IEA cell cycle arrest
GO:0007093 IEA mitotic cell cycle checkpoint
GO:0007264 IDA small GTPase mediated signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0007569 IDA cell aging
GO:0008022 IEA protein C-terminus binding
GO:0008283 IPI cell proliferation
GO:0008284 IGI:IDA positive regulation of cell proliferation
GO:0008285 IEA negative regulation of cell proliferation
GO:0008542 IGI visual learning
GO:0010628 IDA positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0016020 IDA membrane
GO:0030036 IGI actin cytoskeleton organization
GO:0030335 IEA positive regulation of cell migration
GO:0032228 IGI regulation of synaptic transmission, GABAergic
GO:0032403 ISO protein complex binding
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0034259 IEA negative regulation of Rho GTPase activity
GO:0035022 IGI positive regulation of Rac protein signal transduction
GO:0035176 IEA social behavior
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0043410 IEA positive regulation of MAPK cascade
GO:0043524 IGI:IDA negative regulation of neuron apoptotic process
GO:0045596 IDA negative regulation of cell differentiation
GO:0045740 IEA positive regulation of DNA replication
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046330 IEA positive regulation of JNK cascade
GO:0046579 ISO positive regulation of Ras protein signal transduction
GO:0048169 IGI:IMP regulation of long-term neuronal synaptic plasticity
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0051146 IGI striated muscle cell differentiation
GO:0051291 IEA protein heterooligomerization
GO:0060441 IDA epithelial tube branching involved in lung morphogenesis
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0090303 IEA positive regulation of wound healing
GO:0090398 IEA cellular senescence
GO:0097193 IGI intrinsic apoptotic signaling pathway
GO:1900029 IEA positive regulation of ruffle assembly
GO:2000251 IEA positive regulation of actin cytoskeleton reorganization
GO:2000630 IEA positive regulation of miRNA metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005651 hrasb -Ha-ras Harvey rat sarcoma viral oncogene homolog b protein_coding Danio_rerio
ENSDARG00000070524 hrasa v-Ha-ras Harvey rat sarcoma viral oncogene homolog a protein_coding Danio_rerio
ENSG00000174775 HRAS Harvey rat sarcoma viral oncogene homolog protein_coding Homo_sapiens

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