C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chromobox 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025578 Cbx8 10090 - 11:119036305-119040969 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026663 Cbx8-001 119036305-119040969 protein_coding
  ENSMUST00000128019 Cbx8-002 119039053-119040831 processed_transcript
  ENSMUST00000143831 Cbx8-003 119039184-119040911 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026663ENSMUST00000128019ENSMUST00000143831
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026663 0.583±0.24 1.080±0.31 1.212±0.10 1.123±0.61 0.845±0.65 0.592±0.13 0.387±0.08 0.526±0.15 0.469±0.13 0.693±0.20 0.387±0.10 1.247±0.58 2.454±1.12 0.277±0.04
ENSMUST00000128019 N/A N/A N/A N/A N/A 0.465±0.00 N/A N/A 0.477±0.02 N/A 0.540±0.13 N/A 2.447±0.00 N/A
ENSMUST00000143831 1.738±0.47 4.108±1.27 1.725±0.00 2.348±0.00 2.052±0.67 1.259±0.28 0.577±0.07 0.861±0.20 1.078±0.62 1.114±0.42 0.860±0.31 2.821±0.31 10.164±1.60 0.298±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002X9 CIL_0002X9_0002 CGP 11:119022962-119040969
CIL_0002WM CIL_0002WM_0002 CGP 11:119036305-119086221

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000151 IDA ubiquitin ligase complex
GO:0000790 IEA nuclear chromatin
GO:0000792 IDA heterochromatin
GO:0003727 IDA single-stranded RNA binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0006342 ISS chromatin silencing
GO:0006351 IEA transcription, DNA-templated
GO:0016574 IDA histone ubiquitination
GO:0031519 IDA PcG protein complex
GO:0035064 IEA methylated histone binding
GO:0035102 ISS PRC1 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070329 cbx8b chromobox homolog 8b protein_coding Danio_rerio
ENSDARG00000087327 cbx8a chromobox homolog 8a (Pc class homolog, Drosophila) protein_coding Danio_rerio
ENSDARG00000092933 cbx8a chromobox homolog 8a (Pc class homolog, Drosophila) protein_coding Danio_rerio
ENSG00000141570 CBX8 chromobox homolog 8 protein_coding Homo_sapiens

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