C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulatory associated protein of MTOR, complex 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025583 Rptor 10090 + 11:119602905-119899576 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026671 Rptor-003 119603149-119899407 protein_coding
  ENSMUST00000124401 Rptor-009 119822947-119856298 protein_coding
  ENSMUST00000125583 Rptor-008 119602905-119823176 retained_intron
  ENSMUST00000126802 Rptor-005 119811246-119867389 retained_intron
  ENSMUST00000127899 Rptor-004 119655944-119865810 retained_intron
  ENSMUST00000130049 Rptor-002 119602995-119782281 retained_intron
  ENSMUST00000131217 Rptor-011 119857444-119884967 nonsense_mediated_decay
  ENSMUST00000136662 Rptor-006 119856259-119896153 nonsense_mediated_decay
  ENSMUST00000139728 Rptor-007 119798773-119846955 nonsense_mediated_decay
  ENSMUST00000147772 Rptor-012 119603015-119845039 retained_intron
  ENSMUST00000147781 Rptor-001 119603698-119899576 nonsense_mediated_decay
  ENSMUST00000148860 Rptor-010 119856309-119857802 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026671ENSMUST00000147781
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026671 4.601±0.94 11.873±3.88 2.847±0.14 5.377±0.38 5.606±2.42 3.358±1.08 2.628±0.39 3.307±1.05 2.237±0.81 4.459±1.17 5.359±0.81 7.008±2.63 3.977±2.13 1.867±0.73
ENSMUST00000147781 5.692±0.53 6.411±2.13 4.109±1.18 7.965±3.72 5.046±0.39 6.867±1.67 3.996±1.26 4.038±1.05 3.979±1.94 5.681±0.34 1.329±0.41 7.708±3.08 4.443±2.53 7.617±2.96

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00042J CIL_00042J_0002 CGP 11:119538719-119899576
CIL_00042G CIL_00042G_0002 CGP 11:119602905-119919548

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001030 IEA RNA polymerase III type 1 promoter DNA binding
GO:0001031 IEA RNA polymerase III type 2 promoter DNA binding
GO:0001032 IEA RNA polymerase III type 3 promoter DNA binding
GO:0001156 IEA TFIIIC-class transcription factor binding
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0005737 IEA cytoplasm
GO:0005764 IEA lysosome
GO:0005765 IEA lysosomal membrane
GO:0008361 IEA regulation of cell size
GO:0016049 IEA cell growth
GO:0019901 IEA protein kinase binding
GO:0030425 IEA dendrite
GO:0031669 IEA cellular response to nutrient levels
GO:0031929 IEA TOR signaling
GO:0031931 ISO TORC1 complex
GO:0032008 IEA positive regulation of TOR signaling
GO:0032403 IEA protein complex binding
GO:0042325 IEA regulation of phosphorylation
GO:0043025 IEA neuronal cell body
GO:0045945 IEA positive regulation of transcription from RNA polymerase III promoter
GO:0071230 IEA cellular response to amino acid stimulus
GO:0071889 IEA 14-3-3 protein binding
GO:0071902 IEA positive regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059879 rptor regulatory associated protein of MTOR, complex 1 protein_coding Danio_rerio
ENSG00000141564 RPTOR regulatory associated protein of MTOR, complex 1 protein_coding Homo_sapiens

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