C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulatory associated protein of MTOR, complex 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141564 RPTOR 9606 + 17:80544819-80966371 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306801 RPTOR-001 80545268-80966368 protein_coding
  ENST00000544334 RPTOR-006 80545468-80966368 protein_coding
  ENST00000570891 RPTOR-005 80544877-80823620 protein_coding
  ENST00000572733 RPTOR-008 80708933-80754104 processed_transcript
  ENST00000573163 RPTOR-010 80948550-80961444 processed_transcript
  ENST00000573746 RPTOR-007 80545666-80593805 processed_transcript
  ENST00000573837 RPTOR-009 80945567-80949545 retained_intron
  ENST00000574767 RPTOR-004 80544819-80858124 nonsense_mediated_decay
  ENST00000575542 RPTOR-002 80743287-80966371 processed_transcript
  ENST00000576366 RPTOR-011 80922724-80924172 protein_coding
  ENST00000577161 RPTOR-003 80544831-80909867 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306801ENST00000544334ENST00000570891ENST00000574767ENST00000575542ENST00000577161
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306801 2.393±0.00 3.603±0.00 1.188±0.00 4.882±0.00 1.828±0.63 0.933±0.64 2.948±0.00 1.254±0.27 1.387±0.38 1.648±0.49 2.690±0.00 2.283±0.57 3.218±1.26 3.494±0.91
ENST00000544334 2.358±0.00 N/A N/A 2.152±0.00 0.738±0.00 0.914±0.00 0.777±0.00 0.291±0.00 0.719±0.00 N/A 2.513±0.70 N/A 1.056±0.00 N/A
ENST00000570891 N/A N/A N/A N/A 1.219±0.00 0.991±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000574767 N/A N/A N/A N/A N/A N/A N/A 0.731±0.00 N/A N/A N/A N/A N/A N/A
ENST00000575542 N/A N/A N/A 3.006±0.00 2.928±0.00 1.908±0.00 1.062±0.00 1.600±0.00 1.460±0.00 1.328±0.00 4.562±4.21 1.704±0.00 1.320±0.00 2.020±0.00
ENST00000577161 N/A 2.222±0.00 N/A 0.947±0.00 N/A 0.980±0.00 N/A 0.547±0.00 N/A N/A N/A 1.137±0.18 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00042J CIL_00042J_0001 CGP 17:80467148-80966371
CIL_00042G CIL_00042G_0001 CGP 17:80544819-81009517

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001030 IDA RNA polymerase III type 1 promoter DNA binding
GO:0001031 IDA RNA polymerase III type 2 promoter DNA binding
GO:0001032 IDA RNA polymerase III type 3 promoter DNA binding
GO:0001156 IDA TFIIIC-class transcription factor binding
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005764 IDA lysosome
GO:0005765 IDA lysosomal membrane
GO:0005829 TAS cytosol
GO:0007050 TAS cell cycle arrest
GO:0008286 TAS insulin receptor signaling pathway
GO:0008361 IMP regulation of cell size
GO:0016049 IMP cell growth
GO:0019901 IPI protein kinase binding
GO:0030425 IEA dendrite
GO:0031669 IMP cellular response to nutrient levels
GO:0031929 IDA TOR signaling
GO:0031931 IDA TORC1 complex
GO:0032008 IDA positive regulation of TOR signaling
GO:0032403 IPI protein complex binding
GO:0042325 IEA regulation of phosphorylation
GO:0043025 IEA neuronal cell body
GO:0045945 IMP positive regulation of transcription from RNA polymerase III promoter
GO:0071230 IMP cellular response to amino acid stimulus
GO:0071889 IDA 14-3-3 protein binding
GO:0071902 IDA positive regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059879 rptor regulatory associated protein of MTOR, complex 1 protein_coding Danio_rerio
ENSMUSG00000025583 Rptor regulatory associated protein of MTOR, complex 1 protein_coding Mus_musculus

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