C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: isocitrate dehydrogenase 1 (NADP+), soluble
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025950 Idh1 10090 - 1:65158616-65186500 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000097709 Idh1-001 65158616-65179181 protein_coding
  ENSMUST00000149310 Idh1-002 65168589-65175564 protein_coding
  ENSMUST00000169032 Idh1-201 65158618-65186479 protein_coding
  ENSMUST00000186222 Idh1-006 65171120-65186459 protein_coding
  ENSMUST00000188109 Idh1-003 65166199-65186438 protein_coding
  ENSMUST00000188876 Idh1-004 65166244-65186500 protein_coding
  ENSMUST00000191459 Idh1-005 65175296-65186479 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000097709ENSMUST00000169032
Transcript ID Adipose Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000097709 16.097±2.56 65.607±19.64 58.337±37.05 4.438±1.42 3.669±0.48 37.220±7.58 32.240±12.66 5.093±1.35 5.796±0.75 288.467±74.14 29.175±23.14 3.867±1.02
ENSMUST00000169032 N/A N/A N/A N/A 2.421±0.00 N/A N/A N/A 0.615±0.05 N/A N/A 2.137±0.71

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00045J CIL_00045J_0002 CGP 1:65105285-65186500
CIL_00014C CIL_00014C_0002 CGP 1:65158616-65278695

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0004450 IDA:ISS isocitrate dehydrogenase (NADP+) activity
GO:0005102 IEA receptor binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005777 IEA peroxisome
GO:0005829 IDA cytosol
GO:0006097 IEA glyoxylate cycle
GO:0006099 IEA tricarboxylic acid cycle
GO:0006102 IEA:ISS isocitrate metabolic process
GO:0006103 ISS 2-oxoglutarate metabolic process
GO:0006749 IMP glutathione metabolic process
GO:0006979 IDA response to oxidative stress
GO:0008585 IEA female gonad development
GO:0014070 IEA response to organic cyclic compound
GO:0042803 IEA protein homodimerization activity
GO:0048545 IEA response to steroid hormone
GO:0050661 IEA NADP binding
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025375 idh1 isocitrate dehydrogenase 1 (NADP+), soluble protein_coding Danio_rerio
ENSG00000138413 IDH1 isocitrate dehydrogenase 1 (NADP+), soluble protein_coding Homo_sapiens

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