C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NADH dehydrogenase (ubiquinone) Fe-S protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025968 Ndufs1 10090 - 1:63143596-63176833 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027111 Ndufs1-001 63143596-63176822 protein_coding
  ENSMUST00000140612 Ndufs1-002 63158902-63176667 retained_intron
  ENSMUST00000168099 Ndufs1-006 63143735-63176732 protein_coding
  ENSMUST00000185412 Ndufs1-008 63169253-63176793 protein_coding
  ENSMUST00000185732 Ndufs1-010 63165014-63176666 protein_coding
  ENSMUST00000185827 Ndufs1-005 63156683-63176669 retained_intron
  ENSMUST00000185847 Ndufs1-011 63150066-63176663 protein_coding
  ENSMUST00000186569 Ndufs1-004 63150233-63152842 retained_intron
  ENSMUST00000187756 Ndufs1-012 63143689-63147391 nonsense_mediated_decay
  ENSMUST00000187835 Ndufs1-013 63143604-63147723 retained_intron
  ENSMUST00000188370 Ndufs1-007 63163839-63176690 protein_coding
  ENSMUST00000189664 Ndufs1-009 63170853-63176833 protein_coding
  ENSMUST00000190095 Ndufs1-003 63143596-63144961 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000027111ENSMUST00000168099ENSMUST00000185827
Transcript ID Adipose Bladder Brain Breast Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000027111 18.057±0.74 32.347±4.60 23.842±2.13 35.093±14.55 97.923±12.44 31.345±3.99 27.987±13.68 84.882±20.87 42.236±4.13 40.486±8.83 9.548±1.24
ENSMUST00000168099 19.494±0.40 N/A 43.345±0.00 22.956±2.78 73.604±6.81 35.996±3.81 14.189±1.61 48.105±13.09 N/A N/A 9.723±2.01
ENSMUST00000185827 N/A N/A 36.196±0.00 N/A N/A N/A N/A N/A N/A N/A 23.396±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039O CIL_00039O_0002 CGP 1:62958418-63176833
CIL_0001R4 CIL_0001R4_0002 CGP 1:63143596-63180486

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005739 IDA mitochondrion
GO:0005747 ISS mitochondrial respiratory chain complex I
GO:0005758 ISS mitochondrial intermembrane space
GO:0008137 IBA NADH dehydrogenase (ubiquinone) activity
GO:0008637 ISS apoptotic mitochondrial changes
GO:0009055 IEA electron carrier activity
GO:0042773 IEA ATP synthesis coupled electron transport
GO:0045333 ISS cellular respiration
GO:0046034 ISS ATP metabolic process
GO:0046872 IEA metal ion binding
GO:0051537 IEA 2 iron, 2 sulfur cluster binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0051881 ISS regulation of mitochondrial membrane potential
GO:0072593 ISS reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028546 ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 protein_coding Danio_rerio
ENSG00000023228 NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) protein_coding Homo_sapiens

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