C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000023228 NDUFS1 9606 - 2:206114817-206159603 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233190 NDUFS1-001 206114817-206159603 protein_coding
  ENST00000423725 NDUFS1-005 206123819-206159509 protein_coding
  ENST00000432169 NDUFS1-002 206124101-206159425 protein_coding
  ENST00000440274 NDUFS1-003 206123956-206159425 protein_coding
  ENST00000449699 NDUFS1-007 206124101-206159194 protein_coding
  ENST00000454195 NDUFS1-008 206147782-206159257 protein_coding
  ENST00000455934 NDUFS1-201 206123111-206159194 protein_coding
  ENST00000456284 NDUFS1-009 206147646-206159425 nonsense_mediated_decay
  ENST00000457011 NDUFS1-004 206123945-206159425 protein_coding
  ENST00000498520 NDUFS1-010 206127560-206132969 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000233190ENST00000423725ENST00000432169ENST00000440274ENST00000449699
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000233190 3.859±0.00 4.701±0.00 4.454±0.00 8.072±1.40 3.724±1.59 4.804±0.20 14.133±6.61 5.933±1.52 5.573±0.89 2.525±0.00 6.367±2.01 4.204±0.59 N/A 2.702±1.01
ENST00000423725 N/A N/A N/A N/A N/A N/A N/A 13.948±0.00 N/A N/A N/A N/A N/A N/A
ENST00000432169 N/A N/A N/A N/A N/A N/A N/A 29.456±0.00 N/A N/A 22.379±0.00 N/A N/A 18.018±0.00
ENST00000440274 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.957±0.00 8.214±0.00
ENST00000449699 16.203±0.00 N/A 18.920±0.00 32.836±5.61 18.158±4.17 25.301±0.00 76.908±15.31 28.008±0.00 25.903±0.00 11.384±0.00 41.273±8.09 23.667±0.00 N/A 7.652±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039O CIL_00039O_0001 CGP 2:205993721-206159603
CIL_0001R4 CIL_0001R4_0001 CGP 2:206114817-206162928

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0005747 IDA mitochondrial respiratory chain complex I
GO:0005758 IDA mitochondrial intermembrane space
GO:0006120 NAS mitochondrial electron transport, NADH to ubiquinone
GO:0008137 IEA:NAS NADH dehydrogenase (ubiquinone) activity
GO:0008637 IDA apoptotic mitochondrial changes
GO:0009055 IEA:NAS electron carrier activity
GO:0016020 IEA membrane
GO:0016491 IEA oxidoreductase activity
GO:0016651 IEA oxidoreductase activity, acting on NAD(P)H
GO:0022904 TAS respiratory electron transport chain
GO:0042773 IEA ATP synthesis coupled electron transport
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045333 IMP cellular respiration
GO:0046034 IMP ATP metabolic process
GO:0046872 IEA metal ion binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051537 IEA 2 iron, 2 sulfur cluster binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0051881 IMP regulation of mitochondrial membrane potential
GO:0055114 IEA oxidation-reduction process
GO:0072593 IMP reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028546 ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 protein_coding Danio_rerio
ENSMUSG00000025968 Ndufs1 NADH dehydrogenase (ubiquinone) Fe-S protein 1 protein_coding Mus_musculus

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