C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026121 Sema4c 10090 - 1:36548642-36558381 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000114991 Sema4c-201 36548642-36558381 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000114991
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000114991 11.374±2.80 8.368±1.90 13.865±2.60 9.756±3.99 7.135±1.67 3.492±1.15 2.301±0.74 2.501±0.56 1.199±0.76 8.532±1.52 2.058±0.74 9.213±3.66 20.340±10.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UD CIL_0002UD_0002 CGP 1:36538173-36558381
CIL_0002UE CIL_0002UE_0002 CGP 1:36548642-36683183

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 IMP neural tube closure
GO:0004872 IEA receptor activity
GO:0005515 IPI protein binding
GO:0014069 IDA postsynaptic density
GO:0016021 IEA integral component of membrane
GO:0021535 IMP cell migration in hindbrain
GO:0021549 IMP cerebellum development
GO:0030054 IEA cell junction
GO:0030672 IDA synaptic vesicle membrane
GO:0032874 ISS positive regulation of stress-activated MAPK cascade
GO:0042692 IMP muscle cell differentiation
GO:0045211 IEA postsynaptic membrane
GO:0071526 IMP semaphorin-plexin signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079611 SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C protein_coding Danio_rerio
ENSG00000168758 SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C protein_coding Homo_sapiens

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