C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168758 SEMA4C 9606 - 2:96859716-96870757 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305476 SEMA4C-001 96859716-96869971 protein_coding
  ENST00000442264 SEMA4C-006 96865234-96868588 protein_coding
  ENST00000449330 SEMA4C-005 96865667-96870757 protein_coding
  ENST00000467747 SEMA4C-003 96859748-96863328 retained_intron
  ENST00000474420 SEMA4C-004 96859736-96862447 retained_intron
  ENST00000482925 SEMA4C-002 96859742-96866930 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000305476ENST00000467747ENST00000474420ENST00000482925
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000305476 13.869±0.00 11.014±0.00 N/A 7.645±6.74 3.439±1.61 9.649±9.35 1.833±1.08 5.277±0.00 5.228±0.00 19.800±0.00 2.261±0.00 17.889±6.89 38.783±19.67 7.354±0.00
ENST00000467747 N/A 4.977±0.00 0.807±0.00 4.068±0.00 1.823±0.00 N/A 0.698±0.00 1.211±0.00 N/A 0.218±0.00 N/A N/A N/A 1.312±0.22
ENST00000474420 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.716±0.00 N/A N/A
ENST00000482925 N/A 3.771±0.00 N/A N/A 1.054±0.00 N/A 0.290±0.00 N/A 1.102±0.00 4.362±0.00 N/A 3.199±1.27 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UD CIL_0002UD_0001 CGP 2:96836611-96870757
CIL_0002UE CIL_0002UE_0001 CGP 2:96859716-97018438

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 ISS neural tube closure
GO:0004872 IEA receptor activity
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0007275 IEA multicellular organismal development
GO:0014069 ISS postsynaptic density
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0021535 ISS cell migration in hindbrain
GO:0021549 IEA cerebellum development
GO:0030054 IEA cell junction
GO:0030672 ISS synaptic vesicle membrane
GO:0032874 IDA positive regulation of stress-activated MAPK cascade
GO:0042692 IDA muscle cell differentiation
GO:0045211 IEA postsynaptic membrane
GO:0071526 ISS semaphorin-plexin signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079611 SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C protein_coding Danio_rerio
ENSMUSG00000026121 Sema4c sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C protein_coding Mus_musculus

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