C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026180 Cxcr2 10090 + 1:74153989-74161246 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027372 Cxcr2-201 74153989-74160610 protein_coding
  ENSMUST00000106899 Cxcr2-001 74153991-74161246 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027372ENSMUST00000106899
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027372 0.903±0.01 N/A N/A N/A 1.082±0.21 0.050±0.01 0.540±0.06 0.189±0.00 0.772±0.95 2.440±0.41 N/A 0.160±0.01 3.252±0.86 N/A
ENSMUST00000106899 0.242±0.18 0.055±0.02 0.040±0.01 0.190±0.14 0.528±0.31 0.103±0.07 0.173±0.09 0.143±0.07 0.612±0.70 0.762±0.18 0.079±0.09 0.240±0.10 4.913±3.13 0.109±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WL CIL_0007WL_0002 VISTA 1:73730234-74332407
CIL_0005VO CIL_0005VO_0002 CGP 1:74125541-74161246
CIL_0005VN CIL_0005VN_0002 CGP 1:74153989-74194631

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002438 IEA acute inflammatory response to antigenic stimulus
GO:0002690 IEA positive regulation of leukocyte chemotaxis
GO:0004871 IEA signal transducer activity
GO:0004918 TAS interleukin-8 receptor activity
GO:0004950 TAS chemokine receptor activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005886 IEA plasma membrane
GO:0006935 TAS chemotaxis
GO:0006968 IEA cellular defense response
GO:0007165 IEA signal transduction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0008284 IEA positive regulation of cell proliferation
GO:0009986 IEA cell surface
GO:0010666 IEA positive regulation of cardiac muscle cell apoptotic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019959 IEA interleukin-8 binding
GO:0030593 IEA neutrophil chemotaxis
GO:0030901 IEA midbrain development
GO:0031623 IEA receptor internalization
GO:0033030 IEA negative regulation of neutrophil apoptotic process
GO:0038112 TAS interleukin-8-mediated signaling pathway
GO:0042119 IEA neutrophil activation
GO:0042629 IEA mast cell granule
GO:0043066 IMP negative regulation of apoptotic process
GO:0043117 IEA positive regulation of vascular permeability
GO:0045766 IEA positive regulation of angiogenesis
GO:0070098 IEA chemokine-mediated signaling pathway
GO:0072173 IEA metanephric tubule morphogenesis
GO:0090023 IEA positive regulation of neutrophil chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054975 CXCR1 chemokine (C-X-C motif) receptor 1 protein_coding Danio_rerio
ENSG00000180871 CXCR2 chemokine (C-X-C motif) receptor 2 protein_coding Homo_sapiens

Loading