C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thyroid hormone receptor interactor 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026219 Trip12 10090 - 1:84721189-84840516 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027421 Trip12-201 84721189-84839304 protein_coding
  ENSMUST00000185567 Trip12-007 84756649-84760184 retained_intron
  ENSMUST00000185672 Trip12-012 84765951-84766715 retained_intron
  ENSMUST00000185720 Trip12-009 84728607-84731774 retained_intron
  ENSMUST00000185909 Trip12-003 84749219-84839311 nonsense_mediated_decay
  ENSMUST00000186465 Trip12-001 84721189-84840516 protein_coding
  ENSMUST00000186648 Trip12-006 84724264-84839288 protein_coding
  ENSMUST00000186894 Trip12-004 84754403-84839304 protein_coding
  ENSMUST00000187733 Trip12-014 84724577-84731703 nonsense_mediated_decay
  ENSMUST00000187818 Trip12-011 84794231-84838731 protein_coding
  ENSMUST00000189496 Trip12-005 84782827-84839301 protein_coding
  ENSMUST00000189670 Trip12-013 84724264-84749277 protein_coding
  ENSMUST00000189841 Trip12-017 84744728-84754404 nonsense_mediated_decay
  ENSMUST00000190067 Trip12-002 84793987-84840266 protein_coding
  ENSMUST00000190125 Trip12-016 84749158-84750543 retained_intron
  ENSMUST00000190464 Trip12-018 84765987-84793551 protein_coding
  ENSMUST00000190474 Trip12-010 84782361-84784298 retained_intron
  ENSMUST00000191187 Trip12-015 84726210-84728876 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027421ENSMUST00000186465ENSMUST00000186648ENSMUST00000186894ENSMUST00000187733ENSMUST00000189670
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027421 4.859±1.44 2.660±1.29 15.988±0.27 16.319±8.16 4.909±1.56 2.496±0.78 2.557±0.65 5.790±0.91 4.516±1.85 5.398±1.17 5.159±1.51 4.876±2.27 14.264±1.29 9.385±0.50
ENSMUST00000186465 2.859±0.00 N/A N/A 3.349±1.24 N/A N/A N/A N/A N/A N/A N/A 5.928±1.44 11.514±0.00 14.689±0.00
ENSMUST00000186648 2.168±0.00 N/A N/A N/A 2.470±0.00 3.075±0.00 3.155±0.77 2.757±0.00 3.417±1.75 N/A 5.420±0.84 7.816±0.65 25.578±13.27 15.042±2.67
ENSMUST00000186894 N/A N/A N/A N/A N/A 2.670±0.48 3.949±0.20 N/A 2.440±0.00 N/A N/A 2.966±0.00 26.289±2.74 22.720±0.00
ENSMUST00000187733 N/A N/A N/A N/A 24.427±2.01 N/A N/A N/A 14.603±0.00 N/A N/A N/A N/A N/A
ENSMUST00000189670 N/A N/A 18.544±0.96 18.584±0.00 N/A N/A N/A N/A 7.536±1.50 N/A 8.141±1.15 25.419±12.16 67.740±58.33 227.388±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087W CIL_00087W_0002 VISTA 1:84248810-84851347
CIL_00076T CIL_00076T_0002 CGP 1:84369839-84840516
CIL_00076Q CIL_00076Q_0002 CGP 1:84721189-84900487

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005515 IEA protein binding
GO:0005634 IBA nucleus
GO:0005654 ISS nucleoplasm
GO:0005737 IBA cytoplasm
GO:0006281 IEA DNA repair
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0009790 IMP embryo development
GO:0016874 IEA ligase activity
GO:0042787 ISS protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0046966 IEA thyroid hormone receptor binding
GO:1901315 ISS negative regulation of histone H2A K63-linked ubiquitination
GO:2000780 ISS negative regulation of double-strand break repair

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061397 trip12 thyroid hormone receptor interactor 12 protein_coding Danio_rerio
ENSG00000153827 TRIP12 thyroid hormone receptor interactor 12 protein_coding Homo_sapiens

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