C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: natriuretic peptide type C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026241 Nppc 10090 - 1:86666291-86670571 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027449 Nppc-001 86666291-86670571 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027449
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027449 0.695±0.47 0.211±0.06 0.064±0.02 1.668±0.31 0.395±0.07 0.129±0.10 0.055±0.03 0.053±0.03 0.045±0.04 0.091±0.05 0.301±0.16 20.803±10.74 5.457±2.26 0.110±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000899 CIL_000899_0002 VISTA 1:86187174-86788752
CIL_0007WD CIL_0007WD_0002 VISTA 1:86187834-86792789
CIL_0007FO CIL_0007FO_0002 CGP 1:86582904-86670571
CIL_0007FN CIL_0007FN_0002 CGP 1:86666291-87050095

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0001666 IEA response to hypoxia
GO:0003418 IMP growth plate cartilage chondrocyte differentiation
GO:0003419 IMP growth plate cartilage chondrocyte proliferation
GO:0005102 IDA receptor binding
GO:0005184 TAS neuropeptide hormone activity
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0006182 IMP cGMP biosynthetic process
GO:0007168 ISS receptor guanylyl cyclase signaling pathway
GO:0008285 IEA negative regulation of cell proliferation
GO:0009791 IMP post-embryonic development
GO:0030141 IEA secretory granule
GO:0030814 IEA regulation of cAMP metabolic process
GO:0030823 IEA regulation of cGMP metabolic process
GO:0030828 IEA positive regulation of cGMP biosynthetic process
GO:0040014 IMP regulation of multicellular organism growth
GO:0042493 IEA response to drug
GO:0042803 IEA protein homodimerization activity
GO:0044702 IMP single organism reproductive process
GO:0045471 IEA response to ethanol
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045909 IEA positive regulation of vasodilation
GO:0048513 IMP organ development
GO:0048660 IEA regulation of smooth muscle cell proliferation
GO:0050880 IEA regulation of blood vessel size
GO:0051053 IEA negative regulation of DNA metabolic process
GO:0051428 IEA peptide hormone receptor binding
GO:0051447 IMP negative regulation of meiotic cell cycle
GO:1900194 IMP negative regulation of oocyte maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068126 NPPC (1 of 2) natriuretic peptide C protein_coding Danio_rerio
ENSDARG00000090921 NPPC (2 of 2) natriuretic peptide C protein_coding Danio_rerio
ENSG00000163273 NPPC natriuretic peptide C protein_coding Homo_sapiens

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