C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: natriuretic peptide C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163273 NPPC 9606 - 2:231921820-231926403 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295440 NPPC-001 231925385-231926328 protein_coding
  ENST00000409852 NPPC-002 231921820-231926403 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastHeartLiverOvaryPlacentaTestisENST00000295440ENST00000409852
Transcript ID Adrenal Bladder Brain Breast Heart Liver Ovary Placenta Testis
ENST00000295440 2.840±0.00 N/A 3.109±0.00 N/A 0.660±0.05 0.755±0.00 N/A 0.247±0.09 3.878±0.00
ENST00000409852 0.348±0.00 0.064±0.00 0.887±0.09 0.012±0.00 0.210±0.00 N/A 0.298±0.24 0.269±0.19 1.003±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000899 CIL_000899_0001 VISTA 2:231361987-231963495
CIL_0007WD CIL_0007WD_0001 VISTA 2:231362545-231967398
CIL_0007FO CIL_0007FO_0001 CGP 2:231781671-231926403
CIL_0007FN CIL_0007FN_0001 CGP 2:231921820-232344350

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0001666 IEA response to hypoxia
GO:0003418 ISS growth plate cartilage chondrocyte differentiation
GO:0003419 ISS growth plate cartilage chondrocyte proliferation
GO:0005102 IPI receptor binding
GO:0005179 IEA hormone activity
GO:0005576 IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006182 IDA cGMP biosynthetic process
GO:0007168 IDA receptor guanylyl cyclase signaling pathway
GO:0008285 IEA negative regulation of cell proliferation
GO:0009791 IEA post-embryonic development
GO:0030141 IEA secretory granule
GO:0030814 IDA regulation of cAMP metabolic process
GO:0030823 IDA regulation of cGMP metabolic process
GO:0030828 IEA positive regulation of cGMP biosynthetic process
GO:0040014 IEA regulation of multicellular organism growth
GO:0042493 IEA response to drug
GO:0042803 IEA protein homodimerization activity
GO:0044702 IEA single organism reproductive process
GO:0045471 IEA response to ethanol
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045909 IEA positive regulation of vasodilation
GO:0048513 IEA organ development
GO:0048660 IEA regulation of smooth muscle cell proliferation
GO:0050880 IEA regulation of blood vessel size
GO:0051053 IEA negative regulation of DNA metabolic process
GO:0051428 IEA peptide hormone receptor binding
GO:0051447 IDA negative regulation of meiotic cell cycle
GO:1900194 IDA negative regulation of oocyte maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068126 NPPC (1 of 2) natriuretic peptide C protein_coding Danio_rerio
ENSDARG00000090921 NPPC (2 of 2) natriuretic peptide C protein_coding Danio_rerio
ENSMUSG00000026241 Nppc natriuretic peptide type C protein_coding Mus_musculus

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