C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine (or cysteine) peptidase inhibitor, clade B, member 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000112706 Serpinb8-001 ENSMUSG00000026315 10090 + 1:107590006-107610484 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000112706
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000112706 0.833±0.16 0.441±0.18 1.268±0.37 0.065±0.00 0.952±0.44 0.215±0.07 0.253±0.08 1.659±0.00 0.188±0.18 1.415±0.43 0.051±0.00 0.513±0.30 0.069±0.05 0.046±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000160 CIL_000160_000Y CGP 1:107529003-107610484
CIL_00076K CIL_00076K_0002 CGP 1:107590006-110140157

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005737 IBA cytoplasm
GO:0005829 IEA cytosol
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000295211 SERPINB8-003 protein_coding Homo_sapiens 0 309
ENST00000353706 SERPINB8-201 protein_coding Homo_sapiens 0 926
ENST00000397985 SERPINB8-001 protein_coding Homo_sapiens 0 926
ENST00000542677 SERPINB8-202 protein_coding Homo_sapiens 0 798

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