C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026355 Mcm6 10090 - 1:128331590-128359664 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027601 Mcm6-001 128331590-128359664 protein_coding
  ENSMUST00000188755 Mcm6-002 128341023-128343463 retained_intron
  ENSMUST00000190495 Mcm6-004 128331593-128359647 protein_coding
  ENSMUST00000191454 Mcm6-003 128339468-128346042 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027601ENSMUST00000190495ENSMUST00000191454
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027601 8.565±7.36 5.113±0.47 6.828±1.48 12.848±8.31 7.518±1.62 6.366±1.04 1.473±0.10 3.976±1.08 44.416±48.44 5.214±0.58 0.586±0.17 13.687±5.05 29.634±16.36 4.394±0.72
ENSMUST00000190495 0.394±0.05 N/A 0.690±0.12 1.975±0.00 1.421±0.19 0.837±0.26 0.268±0.11 0.340±0.00 0.199±0.06 0.776±0.16 0.105±0.03 1.853±0.41 0.445±0.00 0.440±0.10
ENSMUST00000191454 N/A N/A N/A 2.102±0.00 N/A N/A N/A N/A N/A N/A N/A 28.898±0.00 29.109±20.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006VU CIL_0006VU_0002 CGP 1:128284756-128359664
CIL_0003NC CIL_0003NC_0002 CGP 1:128331590-128417368

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003678 IDA DNA helicase activity
GO:0003697 IPI single-stranded DNA binding
GO:0004003 ISS ATP-dependent DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006268 IPI DNA unwinding involved in DNA replication
GO:0006270 IEA DNA replication initiation
GO:0007049 IEA cell cycle
GO:0042555 ISS MCM complex
GO:0042802 IEA identical protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057683 mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) protein_coding Danio_rerio
ENSG00000076003 MCM6 minichromosome maintenance complex component 6 protein_coding Homo_sapiens

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