C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neurofascin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026442 Nfasc 10090 - 1:132564690-132741797 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043189 Nfasc-001 132569249-132707326 protein_coding
  ENSMUST00000094569 Nfasc-003 132564690-132741757 protein_coding
  ENSMUST00000163770 Nfasc-005 132570334-132741763 protein_coding
  ENSMUST00000186330 Nfasc-014 132576324-132587140 processed_transcript
  ENSMUST00000186389 Nfasc-006 132570423-132637091 protein_coding
  ENSMUST00000186539 Nfasc-013 132601634-132605159 retained_intron
  ENSMUST00000187861 Nfasc-004 132570044-132707406 protein_coding
  ENSMUST00000188307 Nfasc-002 132599835-132741797 protein_coding
  ENSMUST00000189219 Nfasc-011 132664856-132741778 processed_transcript
  ENSMUST00000191294 Nfasc-008 132619380-132624512 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043189ENSMUST00000094569ENSMUST00000163770ENSMUST00000186389ENSMUST00000186539ENSMUST00000187861ENSMUST00000188307
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043189 0.043±0.01 N/A N/A N/A 0.206±0.10 0.207±0.00 0.040±0.00 0.030±0.01 0.047±0.03 0.029±0.01 0.101±0.06 0.161±0.08 0.019±0.01 0.044±0.02
ENSMUST00000094569 0.042±0.02 0.280±0.16 0.521±0.00 13.392±9.09 N/A 0.204±0.10 0.038±0.03 0.027±0.01 0.008±0.01 0.043±0.02 N/A 0.092±0.03 0.022±0.01 0.018±0.01
ENSMUST00000163770 0.040±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.041±0.00 0.154±0.00 0.086±0.00 N/A N/A
ENSMUST00000186389 0.081±0.00 N/A N/A 18.836±0.00 N/A N/A N/A N/A 0.041±0.02 N/A 0.076±0.00 0.155±0.00 0.013±0.00 N/A
ENSMUST00000186539 N/A N/A N/A N/A N/A N/A N/A N/A 0.105±0.02 N/A N/A N/A N/A N/A
ENSMUST00000187861 0.043±0.01 N/A N/A N/A N/A 0.102±0.00 N/A N/A N/A N/A N/A 0.021±0.00 N/A 0.048±0.00
ENSMUST00000188307 0.060±0.00 N/A N/A N/A 0.188±0.00 0.121±0.00 N/A 0.037±0.01 0.037±0.03 0.076±0.02 N/A 0.081±0.01 0.014±0.00 0.055±0.04

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002175 IMP protein localization to paranode region of axon
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005925 IEA focal adhesion
GO:0007411 IDA axon guidance
GO:0007422 IEA peripheral nervous system development
GO:0016021 IEA integral component of membrane
GO:0019226 IMP transmission of nerve impulse
GO:0030424 IDA axon
GO:0030913 IMP paranodal junction assembly
GO:0033010 IDA paranodal junction
GO:0033270 IDA paranode region of axon
GO:0034113 IGI heterotypic cell-cell adhesion
GO:0045162 IMP clustering of voltage-gated sodium channels
GO:0050808 IMP synapse organization
GO:0070062 IEA extracellular vesicular exosome
GO:0071205 IMP protein localization to juxtaparanode region of axon
GO:0086080 IGI protein binding involved in heterotypic cell-cell adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056910 NFASC (1 of 2) neurofascin protein_coding Danio_rerio
ENSDARG00000061099 nfasca neurofascin homolog (chicken) a protein_coding Danio_rerio
ENSG00000163531 NFASC neurofascin protein_coding Homo_sapiens

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