C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Meis homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027210 Meis2 10090 - 2:115863064-116065839 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028639 Meis2-011 115863064-116065047 protein_coding
  ENSMUST00000074285 Meis2-014 115863300-116064512 protein_coding
  ENSMUST00000102538 Meis2-012 115863064-116065047 protein_coding
  ENSMUST00000110906 Meis2-006 115863145-116064721 protein_coding
  ENSMUST00000110907 Meis2-001 115863064-116065839 protein_coding
  ENSMUST00000110908 Meis2-013 115863064-116065839 protein_coding
  ENSMUST00000118654 Meis2-002 115864870-115872962 retained_intron
  ENSMUST00000120995 Meis2-003 115863904-115872943 processed_transcript
  ENSMUST00000133990 Meis2-007 116049084-116064468 processed_transcript
  ENSMUST00000134314 Meis2-008 116049084-116062530 processed_transcript
  ENSMUST00000135543 Meis2-009 116038425-116049212 retained_intron
  ENSMUST00000138526 Meis2-015 116049107-116058842 retained_intron
  ENSMUST00000140461 Meis2-005 115996056-116062360 retained_intron
  ENSMUST00000149217 Meis2-016 115864459-115872943 processed_transcript
  ENSMUST00000150477 Meis2-017 115866876-115872946 processed_transcript
  ENSMUST00000151279 Meis2-010 115864273-116042046 processed_transcript
  ENSMUST00000154671 Meis2-004 115921734-116049680 processed_transcript
  ENSMUST00000177493 Meis2-018 115864318-115872854 processed_transcript
  ENSMUST00000189640 Meis2-020 115864227-115868867 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028639ENSMUST00000074285ENSMUST00000102538ENSMUST00000110906ENSMUST00000110907ENSMUST00000110908ENSMUST00000118654ENSMUST00000120995ENSMUST00000133990ENSMUST00000134314ENSMUST00000140461ENSMUST00000151279ENSMUST00000154671ENSMUST00000177493ENSMUST00000189640
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028639 5.665±0.00 20.774±3.40 N/A N/A N/A 0.785±0.12 1.184±0.00 N/A 0.371±0.10 1.154±0.00 0.006±0.00 N/A 0.999±0.00 0.022±0.00
ENSMUST00000074285 1.612±0.22 N/A 3.962±1.00 20.858±10.35 1.214±0.18 0.998±0.30 2.017±1.05 N/A 0.475±0.06 1.319±0.27 0.053±0.00 3.042±0.59 1.242±0.16 0.150±0.09
ENSMUST00000102538 4.694±3.39 15.146±6.86 5.602±1.20 9.838±0.00 1.047±0.03 0.973±0.00 1.667±0.25 3.638±0.49 0.595±0.20 2.368±0.86 0.087±0.06 3.740±0.73 3.424±1.83 0.079±0.05
ENSMUST00000110906 4.727±2.71 11.632±0.66 2.989±0.00 7.834±0.00 0.917±0.41 1.066±0.39 0.956±0.00 2.311±0.41 0.393±0.23 2.103±0.00 0.125±0.00 5.557±0.78 0.952±0.05 0.055±0.00
ENSMUST00000110907 N/A 11.905±0.00 N/A 11.599±4.03 N/A N/A 0.685±0.00 N/A 0.244±0.09 1.404±0.00 0.048±0.00 N/A 1.241±0.00 N/A
ENSMUST00000110908 4.555±3.81 14.127±3.46 4.302±0.47 16.991±11.97 0.844±0.20 1.235±0.18 0.759±0.00 1.709±0.35 0.394±0.18 1.004±0.27 0.067±0.03 3.764±1.76 2.377±1.08 0.186±0.06
ENSMUST00000118654 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.013±0.00 N/A N/A N/A
ENSMUST00000120995 N/A N/A N/A N/A 2.331±0.00 N/A N/A N/A N/A N/A N/A N/A 14.255±0.00 N/A
ENSMUST00000133990 N/A 54.130±0.00 N/A N/A N/A N/A N/A N/A 0.396±0.00 N/A N/A N/A N/A N/A
ENSMUST00000134314 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.246±0.00 N/A N/A N/A
ENSMUST00000140461 N/A N/A N/A N/A N/A N/A N/A N/A 0.138±0.01 N/A N/A N/A N/A 0.016±0.00
ENSMUST00000151279 N/A N/A N/A N/A N/A N/A 2.816±0.00 N/A N/A N/A 0.183±0.00 N/A N/A 0.501±0.00
ENSMUST00000154671 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.574±0.25
ENSMUST00000177493 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.138±0.00 N/A N/A N/A
ENSMUST00000189640 N/A N/A N/A N/A N/A 5.131±0.76 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007MM CIL_0007MM_0002 UCNEbase 2:114412124-116821493
CIL_00088L CIL_00088L_0002 VISTA 2:115356958-115958248
CIL_0008GX CIL_0008GX_0002 VISTA 2:115358281-115959712
CIL_00084J CIL_00084J_0002 VISTA 2:115369514-115969885
CIL_00087U CIL_00087U_0002 VISTA 2:115567988-116170503
CIL_0008KD CIL_0008KD_0002 VISTA 2:115571243-116172482
CIL_0006QS CIL_0006QS_0002 CGP 2:115581716-116065839
CIL_0008O9 CIL_0008O9_0002 VISTA 2:115596429-116199400
CIL_0008M1 CIL_0008M1_0002 VISTA 2:115619997-116221651
CIL_00096Q CIL_00096Q_0002 VISTA 2:115662485-116263540
CIL_0009D1 CIL_0009D1_0002 VISTA 2:115718048-116320475
CIL_00086F CIL_00086F_0002 VISTA 2:115744886-116346285
CIL_0006QR CIL_0006QR_0002 CGP 2:115863064-116892494

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001654 IGI eye development
GO:0003677 IDA DNA binding
GO:0003712 IDA transcription cofactor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008134 IDA transcription factor binding
GO:0009612 IEA response to mechanical stimulus
GO:0031016 IEA pancreas development
GO:0043565 IGI sequence-specific DNA binding
GO:0045638 IDA negative regulation of myeloid cell differentiation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0070848 IEA response to growth factor

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042361 meis2a myeloid ecotropic viral integration site 2a protein_coding Danio_rerio
ENSDARG00000091279 Meis homeobox 2 protein_coding Danio_rerio
ENSG00000134138 MEIS2 Meis homeobox 2 protein_coding Homo_sapiens

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