C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Meis homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134138 MEIS2 9606 - 15:36889204-37101299 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000314177 MEIS2-012 36891085-37099721 nonsense_mediated_decay
  ENST00000338564 MEIS2-002 36889204-37101205 protein_coding
  ENST00000340545 MEIS2-201 36891022-37101299 protein_coding
  ENST00000397620 MEIS2-005 36891848-37099396 protein_coding
  ENST00000397624 MEIS2-007 36891021-37098321 protein_coding
  ENST00000424352 MEIS2-003 36891850-37100530 protein_coding
  ENST00000557796 MEIS2-017 36891410-37099306 protein_coding
  ENST00000557992 MEIS2-026 36894418-36895302 retained_intron
  ENST00000558313 MEIS2-018 37083790-37101279 protein_coding
  ENST00000558643 MEIS2-022 36894707-36897150 retained_intron
  ENST00000559085 MEIS2-008 36891256-37098302 protein_coding
  ENST00000559129 MEIS2-014 37094516-37096191 retained_intron
  ENST00000559371 MEIS2-027 36892436-36897076 retained_intron
  ENST00000559408 MEIS2-023 36894784-36904067 processed_transcript
  ENST00000559561 MEIS2-028 36894752-37099721 protein_coding
  ENST00000559972 MEIS2-020 36892056-36895287 retained_intron
  ENST00000560570 MEIS2-009 36891256-37099482 nonsense_mediated_decay
  ENST00000560617 MEIS2-015 37083772-37097367 protein_coding
  ENST00000560697 MEIS2-021 37083804-37096506 protein_coding
  ENST00000560702 MEIS2-016 36891032-36898339 retained_intron
  ENST00000561163 MEIS2-006 37036391-37098531 retained_intron
  ENST00000561208 MEIS2-001 36889204-37099885 protein_coding
  ENST00000561264 MEIS2-024 36892130-36895278 retained_intron
  ENST00000561284 MEIS2-025 36892219-36898435 retained_intron
  ENST00000561422 MEIS2-013 37083770-37094029 retained_intron
  ENST00000606653 MEIS2-031 37066297-37094565 protein_coding
  ENST00000607277 MEIS2-030 36895149-37095021 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000314177ENST00000338564ENST00000340545ENST00000397620ENST00000397624ENST00000424352ENST00000559085ENST00000559561ENST00000559972ENST00000560570ENST00000560617ENST00000560702ENST00000561163ENST00000561208ENST00000561284ENST00000607277
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000314177 N/A N/A N/A N/A 7.121±0.00 N/A N/A N/A N/A N/A N/A 1.249±0.71 0.614±0.00
ENST00000338564 N/A N/A 0.810±0.00 0.709±0.00 N/A 0.608±0.00 0.349±0.00 N/A N/A N/A N/A N/A N/A
ENST00000340545 N/A N/A N/A N/A 0.745±0.00 0.830±0.00 N/A 0.673±0.00 N/A N/A 2.336±1.37 1.318±0.13 0.370±0.00
ENST00000397620 N/A N/A N/A 1.371±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000397624 2.433±0.00 N/A 4.221±1.64 1.602±0.00 6.402±5.58 3.627±0.00 2.470±0.00 2.195±1.35 1.633±0.00 0.245±0.00 3.421±1.62 1.782±0.47 1.585±0.00
ENST00000424352 N/A 1.225±0.00 N/A 0.721±0.10 0.668±0.00 0.811±0.00 0.309±0.00 3.426±0.00 N/A N/A N/A 0.760±0.00 N/A
ENST00000559085 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.744±0.00 N/A N/A
ENST00000559561 N/A N/A N/A N/A N/A N/A 6.260±0.00 6.944±0.00 N/A N/A 2.162±0.00 2.734±0.00 N/A
ENST00000559972 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.447±0.00
ENST00000560570 1.564±0.00 N/A N/A N/A N/A 3.440±0.00 N/A 4.423±0.00 N/A N/A N/A 0.505±0.00 N/A
ENST00000560617 N/A 9.479±0.00 N/A N/A N/A N/A N/A N/A N/A 1.757±0.00 N/A N/A N/A
ENST00000560702 N/A 1.230±0.00 N/A 0.681±0.18 1.098±0.00 0.851±0.00 N/A 4.055±0.00 1.389±0.00 N/A 1.411±0.00 N/A N/A
ENST00000561163 N/A N/A N/A 2.504±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000561208 N/A N/A 1.384±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000561284 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.699±0.00 N/A N/A N/A
ENST00000607277 N/A N/A 6.095±0.00 4.614±0.00 5.963±0.00 5.249±0.00 N/A N/A 5.956±0.00 0.683±0.00 26.374±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007MM CIL_0007MM_0001 UCNEbase 15:35253766-37880700
CIL_00088L CIL_00088L_0001 VISTA 15:36372618-36973897
CIL_0008GX CIL_0008GX_0001 VISTA 15:36373931-36975330
CIL_00084J CIL_00084J_0001 VISTA 15:36391617-36991995
CIL_0006QS CIL_0006QS_0001 CGP 15:36579611-37101299
CIL_00087U CIL_00087U_0001 VISTA 15:36595901-37198492
CIL_0008KD CIL_0008KD_0001 VISTA 15:36599207-37200420
CIL_0008O9 CIL_0008O9_0001 VISTA 15:36624792-37227400
CIL_0008M1 CIL_0008M1_0001 VISTA 15:36648604-37250297
CIL_00096Q CIL_00096Q_0001 VISTA 15:36695888-37296972
CIL_0009D1 CIL_0009D1_0001 VISTA 15:36755403-37357754
CIL_00086F CIL_00086F_0001 VISTA 15:36779528-37380936
CIL_0006QR CIL_0006QR_0001 CGP 15:36889204-37967724

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001654 IEA eye development
GO:0003677 IEA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0003712 ISS transcription cofactor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0008134 ISS transcription factor binding
GO:0009612 IEA response to mechanical stimulus
GO:0031016 IEA pancreas development
GO:0043565 IDA sequence-specific DNA binding
GO:0045638 ISS negative regulation of myeloid cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0070848 IEA response to growth factor

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042361 meis2a myeloid ecotropic viral integration site 2a protein_coding Danio_rerio
ENSDARG00000091279 Meis homeobox 2 protein_coding Danio_rerio
ENSMUSG00000027210 Meis2 Meis homeobox 2 protein_coding Mus_musculus

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