C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: midkine
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027239 Mdk 10090 - 2:91929805-91932297 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028672 Mdk-001 91929828-91932297 protein_coding
  ENSMUST00000069423 Mdk-002 91929828-91931780 protein_coding
  ENSMUST00000090602 Mdk-003 91929966-91931699 protein_coding
  ENSMUST00000111309 Mdk-004 91929805-91931688 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028672ENSMUST00000069423ENSMUST00000090602ENSMUST00000111309
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028672 N/A 0.156±0.04 N/A N/A 1.529±0.00 0.472±0.39 N/A N/A 0.134±0.05 N/A 0.239±0.13 5.242±0.93 4.296±0.00 2.385±0.08
ENSMUST00000069423 56.978±51.89 0.724±0.37 17.955±2.63 99.212±32.03 5.544±2.52 1.773±0.54 1.954±0.56 38.635±3.07 8.891±9.95 4.416±0.38 0.507±0.44 43.407±13.40 47.051±33.50 2.972±0.56
ENSMUST00000090602 N/A 0.197±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.536±0.00 13.558±4.05 0.969±0.04
ENSMUST00000111309 N/A 0.816±0.00 N/A N/A N/A N/A N/A N/A 1.410±0.89 0.669±0.00 0.375±0.21 18.009±5.04 48.527±35.54 0.915±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001662 IMP behavioral fear response
GO:0005576 IEA extracellular region
GO:0005737 IEA cytoplasm
GO:0007614 IMP short-term memory
GO:0008083 IEA growth factor activity
GO:0008201 ISS heparin binding
GO:0009611 IDA response to wounding
GO:0009725 IEA response to hormone
GO:0016477 IEA cell migration
GO:0021542 IEP dentate gyrus development
GO:0021681 IMP cerebellar granular layer development
GO:0021766 IMP hippocampus development
GO:0021987 IEP cerebral cortex development
GO:0030154 IEA cell differentiation
GO:0030325 ISS adrenal gland development
GO:0030421 IMP defecation
GO:0042493 IEA response to drug
GO:0042995 IEA cell projection
GO:0043524 IDA negative regulation of neuron apoptotic process
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0050795 IMP regulation of behavior
GO:0051384 IEA response to glucocorticoid
GO:0051781 IEA positive regulation of cell division
GO:1901215 IDA negative regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020708 mdkb midkine-related growth factor b protein_coding Danio_rerio
ENSDARG00000036036 mdka midkine-related growth factor protein_coding Danio_rerio
ENSG00000110492 MDK midkine (neurite growth-promoting factor 2) protein_coding Homo_sapiens

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