C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027304 Rtf1 10090 + 2:119675068-119735407 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028767 Rtf1-001 119675068-119735407 protein_coding
  ENSMUST00000126984 Rtf1-004 119726684-119727652 retained_intron
  ENSMUST00000136321 Rtf1-002 119675072-119692221 processed_transcript
  ENSMUST00000149904 Rtf1-003 119710996-119712462 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028767
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028767 4.361±1.46 4.508±3.16 7.856±0.23 14.479±1.40 4.513±1.49 4.111±1.68 4.224±0.65 4.662±1.24 4.746±2.50 4.322±0.95 6.834±0.18 6.573±3.09 21.855±15.17 5.892±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005FB CIL_0005FB_0002 CGP 2:119655446-119735407
CIL_0005FC CIL_0005FC_0002 CGP 2:119675068-119751263

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001711 IMP endodermal cell fate commitment
GO:0003697 ISS single-stranded DNA binding
GO:0005515 IEA protein binding
GO:0005730 IDA nucleolus
GO:0006352 IEA DNA-templated transcription, initiation
GO:0016055 IEA Wnt signaling pathway
GO:0016593 ISS Cdc73/Paf1 complex
GO:0019827 IMP stem cell maintenance
GO:0032968 ISS positive regulation of transcription elongation from RNA polymerase II promoter
GO:0044822 IEA poly(A) RNA binding
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0051571 IMP positive regulation of histone H3-K4 methylation
GO:0080182 IMP histone H3-K4 trimethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008947 rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) protein_coding Danio_rerio
ENSG00000137815 RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) protein_coding Homo_sapiens

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