C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal peptide peptidase like 2A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027366 Sppl2a 10090 - 2:126890391-126933235 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028844 Sppl2a-001 126890391-126933235 protein_coding
  ENSMUST00000125592 Sppl2a-002 126914874-126923688 retained_intron
  ENSMUST00000143700 Sppl2a-003 126894264-126920345 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028844ENSMUST00000143700
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028844 10.563±1.00 19.523±1.71 14.626±4.36 6.362±3.85 13.243±2.10 22.538±4.95 8.199±0.48 12.924±1.49 18.570±8.93 15.495±0.86 8.249±2.77 10.966±2.90 3.823±2.16 2.773±0.41
ENSMUST00000143700 N/A N/A N/A N/A 14.875±0.00 N/A N/A N/A N/A N/A N/A N/A 6.088±1.32 7.266±1.67

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002DX CIL_0002DX_0002 CGP 2:126791565-126933235
CIL_00024D CIL_00024D_0002 CGP 2:126890391-127067909

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004190 IEA aspartic-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005765 IDA lysosomal membrane
GO:0005886 IEA plasma membrane
GO:0006509 ISS membrane protein ectodomain proteolysis
GO:0030660 ISS Golgi-associated vesicle membrane
GO:0031293 ISS membrane protein intracellular domain proteolysis
GO:0031902 IDA late endosome membrane
GO:0042803 ISS protein homodimerization activity
GO:0050776 ISS regulation of immune response
GO:0070062 IEA extracellular vesicular exosome
GO:0071458 ISS integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 ISS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000138600 SPPL2A signal peptide peptidase like 2A protein_coding Homo_sapiens

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