C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: signal peptide peptidase like 2A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000028844 Sppl2a-001 ENSMUSG00000027366 10090 - 2:126890391-126933235 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028844
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028844 10.563±1.00 19.523±1.71 14.626±4.36 6.362±3.85 13.243±2.10 22.538±4.95 8.199±0.48 12.924±1.49 18.570±8.93 15.495±0.86 8.249±2.77 10.966±2.90 3.823±2.16 2.773±0.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002DX CIL_0002DX_0002 CGP 2:126791565-126933235
CIL_00024D CIL_00024D_0002 CGP 2:126890391-127067909

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004190 IEA aspartic-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005765 IDA lysosomal membrane
GO:0005886 IEA plasma membrane
GO:0006509 ISS membrane protein ectodomain proteolysis
GO:0030660 ISS Golgi-associated vesicle membrane
GO:0031293 ISS membrane protein intracellular domain proteolysis
GO:0031902 IDA late endosome membrane
GO:0042803 ISS protein homodimerization activity
GO:0050776 ISS regulation of immune response
GO:0070062 IEA extracellular vesicular exosome
GO:0071458 ISS integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 ISS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000261854 SPPL2A-001 protein_coding Homo_sapiens 0 1467
ENST00000558414 SPPL2A-003 protein_coding Homo_sapiens 0 451
ENST00000558934 SPPL2A-004 protein_coding Homo_sapiens 0 577
ENST00000560288 SPPL2A-002 retained_intron Homo_sapiens 0 298
ENST00000560489 RP11-295H24.3-001 processed_pseudogene Homo_sapiens 0 1262

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