C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SKI-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027660 Skil 10090 + 3:31095058-31122577 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029194 Skil-201 31095061-31122577 protein_coding
  ENSMUST00000117728 Skil-003 31095125-31119280 protein_coding
  ENSMUST00000118204 Skil-002 31096833-31118991 protein_coding
  ENSMUST00000118470 Skil-001 31095058-31122577 protein_coding
  ENSMUST00000123532 Skil-005 31095065-31097892 protein_coding
  ENSMUST00000144756 Skil-004 31095061-31101393 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029194ENSMUST00000117728ENSMUST00000118204ENSMUST00000118470
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029194 0.379±0.00 1.164±0.55 N/A 2.571±0.17 0.912±0.25 2.484±0.48 0.805±0.29 0.806±0.18 0.406±0.09 1.173±0.09 0.770±0.30 2.790±1.80 0.969±0.00 0.661±0.20
ENSMUST00000117728 N/A N/A N/A 7.172±0.00 N/A N/A N/A N/A N/A N/A N/A 15.831±0.00 6.941±4.17 2.248±0.00
ENSMUST00000118204 N/A N/A N/A 10.772±0.00 N/A N/A N/A N/A N/A N/A N/A 11.578±0.00 4.292±1.67 1.604±1.16
ENSMUST00000118470 1.651±1.02 1.328±0.51 4.593±0.38 2.789±0.25 2.047±1.14 3.473±1.56 0.833±0.43 1.873±0.33 1.608±0.89 3.387±1.49 0.504±0.22 4.164±1.96 3.744±1.52 0.399±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XK CIL_0002XK_0002 CGP 3:30995747-31122577
CIL_0002Z6 CIL_0002Z6_0002 CGP 3:31095058-31164324

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001669 IEA acrosomal vesicle
GO:0001825 IMP blastocyst formation
GO:0002260 IMP lymphocyte homeostasis
GO:0003682 IDA chromatin binding
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IBA cytoplasm
GO:0007050 IMP cell cycle arrest
GO:0007179 IGI transforming growth factor beta receptor signaling pathway
GO:0007283 IEA spermatogenesis
GO:0007519 IEA skeletal muscle tissue development
GO:0016605 IEA PML body
GO:0019904 IEA protein domain specific binding
GO:0030512 IMP negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032403 IEA protein complex binding
GO:0034097 IEA response to cytokine
GO:0043234 ISO protein complex
GO:0045596 IDA negative regulation of cell differentiation
GO:0046332 IBA SMAD binding
GO:0046677 IEA response to antibiotic
GO:0050772 IEA positive regulation of axonogenesis
GO:0070207 IEA protein homotrimerization
GO:0070208 IEA protein heterotrimerization
GO:0070306 IDA lens fiber cell differentiation
GO:0070848 IEA response to growth factor
GO:1902043 IMP positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902231 IMP positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022904 skilb SKI-like oncogene b protein_coding Danio_rerio
ENSDARG00000023933 skila SKI-like oncogene a protein_coding Danio_rerio
ENSG00000136603 SKIL SKI-like proto-oncogene protein_coding Homo_sapiens

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