C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glycine receptor, beta subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028020 Glrb 10090 - 3:80843599-80913660 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029654 Glrb-001 80843599-80913660 protein_coding
  ENSMUST00000107743 Glrb-003 80855629-80913528 protein_coding
  ENSMUST00000132330 Glrb-002 80862110-80913589 nonsense_mediated_decay
  ENSMUST00000135043 Glrb-004 80843599-80913614 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029654ENSMUST00000107743ENSMUST00000132330ENSMUST00000135043
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029654 2.444±1.64 2.712±0.34 0.396±0.08 4.215±0.18 0.294±0.10 0.431±0.04 N/A 0.188±0.06 0.058±0.02 0.129±0.03 0.013±0.01 0.923±0.54 0.067±0.05 0.072±0.00
ENSMUST00000107743 N/A N/A N/A N/A 0.157±0.00 N/A N/A N/A 0.047±0.00 N/A 0.034±0.01 N/A 0.106±0.08 N/A
ENSMUST00000132330 N/A N/A N/A N/A N/A N/A N/A 0.281±0.00 N/A N/A N/A N/A N/A 0.143±0.00
ENSMUST00000135043 0.440±0.31 N/A N/A N/A 0.308±0.19 0.470±0.00 0.085±0.05 0.087±0.06 0.033±0.01 0.200±0.06 0.019±0.01 1.313±0.57 0.118±0.11 0.066±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007F1 CIL_0007F1_0002 CGP 3:80684936-80913660

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001964 ISS startle response
GO:0005515 IPI protein binding
GO:0005783 ISA endoplasmic reticulum
GO:0006811 ISS ion transport
GO:0006821 IMP chloride transport
GO:0007218 ISS neuropeptide signaling pathway
GO:0007268 ISS synaptic transmission
GO:0007340 IMP acrosome reaction
GO:0007399 ISS nervous system development
GO:0007601 IMP visual perception
GO:0007628 IMP adult walking behavior
GO:0008144 IPI drug binding
GO:0009897 ISA external side of plasma membrane
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016594 IMP glycine binding
GO:0016933 ISS extracellular-glycine-gated ion channel activity
GO:0016934 IMP extracellular-glycine-gated chloride channel activity
GO:0030054 IEA cell junction
GO:0034220 ISS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0042391 IMP regulation of membrane potential
GO:0045211 IEA postsynaptic membrane
GO:0050905 IMP neuromuscular process
GO:0051291 IEA protein heterooligomerization
GO:0060012 IMP synaptic transmission, glycinergic
GO:0060013 IMP righting reflex
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052769 glrbb glycine receptor, beta b protein_coding Danio_rerio
ENSDARG00000052782 glrba gylcine receptor, beta a protein_coding Danio_rerio
ENSG00000109738 GLRB glycine receptor, beta protein_coding Homo_sapiens

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